1357899-31-0Relevant articles and documents
Design, synthesis and evaluation of caffeic acid phenethyl ester-based inhibitors targeting a selectivity pocket in the active site of human aldo-keto reductase 1B10
Soda, Midori,Hu, Dawei,Endo, Satoshi,Takemura, Mayuko,Li, Jie,Wada, Ryogo,Ifuku, Syohei,Zhao, Hai-Tao,El-Kabbani, Ossama,Ohta, Shozo,Yamamura, Keiko,Toyooka, Naoki,Hara, Akira,Matsunaga, Toshiyuki
, p. 321 - 329 (2012/03/22)
Inhibitors of a human aldo-keto reductase, AKR1B10, are regarded as promising therapeutics for the treatment of cancer, but those with both high potency and selectivity compared to the structurally similar aldose reductase (AKR1B1) have not been reported.