74882-15-8

Basic information

• Product Name: 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol
• Synonyms: 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol
• CAS NO: 74882-15-8
• Molecular Formula: C₁₁H₁₆O₃
• Molecular Weight: 196.24294
• Mol File: 74882-15-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol(74882-15-8)
• EPA Substance Registry System: 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol(74882-15-8)

Safety Data

• Hazardous Substances Data: 74882-15-8(Hazardous Substances Data)

Usage

General Description

3-(4-(MethoxyMethoxy)phenyl)propan-1-ol is a chemical compound with the molecular formula C11H16O3. It is a clear, colorless liquid with a faint, sweet odor. 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol is commonly used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It has also been studied for its potential antifungal and antimicrobial properties. Additionally, 3-(4-(MethoxyMethoxy)phenyl)propan-1-ol has been used in the development of fragrance and flavor compounds. The compound is considered to have low toxicity and is relatively stable under normal conditions.

Upstream product

• 155997-94-7 methyl 3-<4-<(methoxymethylene)oxy>phenyl>-1-propanoate 
• 61440-45-7 3-[4-(benzyloxy)phenyl]propan-1-ol 
• 50463-48-4 3-(4-benzyloxyphenyl)propanoic acid 
• 501-97-3 4-hydroxyphenylpropionic acid 
• 10210-17-0 3-(4-hydroxyphenyl)propan-1-ol 
• 5597-50-2 3-(4-hydroxyphenyl)propionic acid methyl ester 
• 107-30-2 chloromethyl methyl ether 
• 155997-96-9 3-<4-(methoxymethoxy)phenyl>propionic acid 

Downstream Products

• 20711-53-9 p-hydroxy-cinnamaldehyde 
• 1108180-73-9 3-(4-methoxymethoxyphenyl)propylamine 
• 1357899-31-0 3-(2-methoxy-4-methoxymethoxyphenyl)acrylic acid 3-(4-methoxymethoxyphenyl)propyl ester 
• 74882-25-0 (+/-)-1-(4-methoxymethoxyphenyl)-7-(2-benzoyloxy-3,4-dimethoxyphenyl)heptan-3-ol 
• 79422-49-4 1,7-bis(3-iodo-4-(methoxymethoxy)phenyl)-4-hepten-3-one 
• 79422-45-0 1,7-bis(4-(methoxymethoxy)phenyl)-5-hydroxy-3-heptanone 
• 79422-47-2 1,7-bis(4-(methoxymethoxy)phenyl)-4-hepten-3-one 

Relevant articles and documents

Novel drug isolated from mistletoe (1: E,4 E)-1,7-bis(4-hydroxyphenyl)hepta-1,4-dien-3-one for potential treatment of various cancers: Synthesis, pharmacokinetics and pharmacodynamics

(1E,4E)-1,7-Bis(4-hydroxyphenyl)hepta-1,4-dien-3-one (DHDK) is a novel curcuminoid analogue isolated from mistletoe. DHDK exhibits better anti-tumour activity, higher bioavailability and superior stability than curcumin. DHDK is difficult to isolate from Viscum coloratum, but it can be synthesised. MTT (methylthiazolyldiphenyl tetrazolium bromide) assay was used to evaluate the in vitro cytotoxic activity of synthesised DHDK on 12 cancer cell lines. Results showed that DHDK exhibited excellent potential as an anticancer agent, especially for breast and lung cancer. Efficacy was further evaluated in vivo by using MCF-7 breast cancer models. DHDK showed a dose-dependent relationship without weight reduction, mortality growth inhibition or tissue toxicity. Pharmacokinetics and tissue distribution statistics were determined by LC-ESI-MS/MS. This work provided preliminary data on this natural compound and could open up new prospects for changing related parameters to improve drug efficacy.

The reaction of acetal-type protective groups in combination with TMSOTf and 2,2′-bipyridyl; Mild and chemoselective deprotection and direct conversion to other protective groups

A mild and chemoselective deprotection method of various acetal-type protective groups, such as MOM, MEM, BOM, and SEM ethers, has been developed. The combination of TMSOTf and 2,2′-bipyridyl was very effective for the deprotection, and the reaction proceeded via the formation of pyridinium intermediates, which were hydrolyzed to the corresponding alcohols in good to high yields. The features of this method are mild (almost neutral) reaction conditions and the tolerability of acid-sensitive functional groups. This method is also applicable for the direct conversion of MOM ether to BOM or SEM ether using the appropriate alcohols instead of H2O.

A Soluble Polymer Approach to the "Fishing Out" Principle: Synthesis and Purification of β-Amino Alcohols

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