135967-50-9

Basic information

• Product Name: (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one
• Synonyms: (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one
• CAS NO: 135967-50-9
• Molecular Weight: 251.369
• Mol File: 135967-50-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one(135967-50-9)
• EPA Substance Registry System: (5S,6S)-6-Cyclohexylmethyl-3-isopropylidene-5-hydroxypiperidine-2-one(135967-50-9)

Safety Data

• Hazardous Substances Data: 135967-50-9(Hazardous Substances Data)

Upstream product

• 135967-49-6 (S)-6-Cyclohexyl-2-isopropylidene-4-oxo-5-(trityl-amino)-hexanoic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 135967-46-3 Dimethyl 3(S)-4-Cyclohexyl-3-(N-triphenylmethyl)amino-2-oxobutylphosphonate 
• 135967-48-5 (6S)-7-Cyclohexyl-2-methyl-6-(N-triphenylmethyl)-amino-5-oxohept-2-ene-3-oic acid 
• 135967-47-4 (E)-(S)-6-Cyclohexyl-2-isopropyl-4-oxo-5-(trityl-amino)-hex-2-enoic acid methyl ester 
• 3715-29-5 sodium 3-methyl-2-oxobutyrate 
• 123381-13-5 N-Triphenylmethyl-cyclohexylalanine methyl ester 
• 40056-18-6 methyl L-cyclohexylalaninate 
• 27527-05-5 L-cyclohexylalanine 
• 63-91-2 L-phenylalanine 
• 3952-67-8 methyl 3-methyl-2-ketobutanoate 
• 135967-45-2 (S)-6-Cyclohexylmethyl-3-isopropylidene-piperidine-2,5-dione 

Downstream Products

• 125816-10-6 <3S-<3α,5β(R^*)>>-5-(2-Cyclohexyl-1-aminoethyl)dihydro-3-isopropyl-2(3H)-furanone 
• 142687-80-7 (3S,5S,6S)-6-Cyclohexylmethyl-5-hydroxy-3-isopropylpiperidin-2-one 

Relevant articles and documents

Renin inhibitors

A renin inhibiting compound of the formula: STR1 wherein X is O, NH or S and G is a mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof; with the proviso that the compound is not N-(3-(4-M

The stereospecific preparation of a hydroxyethylene isostere precursor via a novel piperidine-2,5-dione template

Hydroxyethylene isostere precursor 2 was synthesized by stereochemical manipulation of a novel ketolactam 'template'. The final product was prepared in very high enantiomeric purity, in 23% overall yield from L-phenylalanine.