1361250-48-7

Basic information

• Product Name: (2S/R,8R)-11-(tert-butyldimethylsilyloxy)-8-hydroxyundec-6-yn-2-yl benzoate
• Synonyms: (2S/R,8R)-11-(tert-butyldimethylsilyloxy)-8-hydroxyundec-6-yn-2-yl benzoate
• CAS NO: 1361250-48-7
• Molecular Weight: 418.649
• Mol File: 1361250-48-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S/R,8R)-11-(tert-butyldimethylsilyloxy)-8-hydroxyundec-6-yn-2-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (2S/R,8R)-11-(tert-butyldimethylsilyloxy)-8-hydroxyundec-6-yn-2-yl benzoate(1361250-48-7)
• EPA Substance Registry System: (2S/R,8R)-11-(tert-butyldimethylsilyloxy)-8-hydroxyundec-6-yn-2-yl benzoate(1361250-48-7)

Safety Data

• Hazardous Substances Data: 1361250-48-7(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 69177-44-2 6-hydroxy-1-heptyne 
• 87184-99-4 4-tert-butyldimethylsilyloxybutan-1-ol 
• 87184-81-4 4-(tert-butyldimethylsilanyloxy)butanal 
• 742078-66-6 (±)-hept-6-yn-2-yl benzoate 
• 928-39-2 hept-6-yn-2-one 
• 1193-18-6 3-methylcyclohexen-2-one 
• 21889-89-4 2,3-epoxy-3-methylcyclohexanone 

Relevant articles and documents

Transition-metal-catalyzed synthesis of aspergillide B: An alkyne addition strategy

A catalytic enantioselective formal total synthesis of aspergillide B is reported. This linchpin synthesis was enabled by the development of new conditions for Zn-ProPhenol catalyzed asymmetric alkyne addition. This reaction was used in conjunction with ruthenium-catalyzed trans-hydrosilylation to affect the rapid construction of a late-stage synthetic intermediate of aspergillide B to complete a formal synthesis of aspergillide B in a highly efficient manner.