1365640-52-3

Basic information

• Product Name: C₂₄H₂₅N₅O₄S
• CAS NO: 1365640-52-3
• Molecular Weight: 479.56
• Mol File: 1365640-52-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₂₅N₅O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₂₅N₅O₄S(1365640-52-3)
• EPA Substance Registry System: C₂₄H₂₅N₅O₄S(1365640-52-3)

Safety Data

• Hazardous Substances Data: 1365640-52-3(Hazardous Substances Data)

Upstream product

• 15783-48-9 2,4-dichlorofuro[3,4-d]pyrimidin-7(5H)-one 
• 4156-75-6 2,4-dihydroxyfuro[3,4-d]pyrimidin-7(5H)-one 
• 55276-43-2 4-methanesulfonylpiperazine 
• 1079651-75-4 4-(benzhydryl-amino)-2-chloro-5H-furo[3,4-d]pyrimidin-7-one 

Downstream Products

• 1079655-05-2 4-(benzhydryl-amino)-6-isopropyl-2-(4-methanesulfonyl-piperazin-1-yl)-5,6-dihydro-pyrrolo[3,4-d]pyrimidin-7-one 

Relevant articles and documents

Discovery of P2X3 selective antagonists for the treatment of chronic pain

Purinergic receptor P2X3 has been linked to analgesia in a number of pre-clinical models of pain, and is expressed in the human pain perception pathway. Only few P2X3-selective antagonists have been reported to date. This Letter describes the SAR and in vivo analgesic profile of a novel scaffold of selective P2X3 antagonists.