136812-19-6Relevant articles and documents
QUINOLINE AND QUINAZOLINE AMIDES AS MODULATORS OF SODIUM CHANNELS
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Paragraph 00632, (2014/08/19)
The invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels: formula (I). The invention also provides pharmaceutically acceptable compositions comprising the compounds of the inve
An efficient approach to heterocyclic analogues of xanthone: A short synthesis of all possible pyrido[5,6]pyrano[2,3-c]pyrazol-4(1H)-ones
Eller, Gernot A.,Wimmer, Veronika,Haring, Andreas W.,Holzer, Wolfgang
, p. 4219 - 4229 (2008/09/16)
An efficient and generally applicable synthesis of various [5,6]pyrano[2,3-c]pyrazol-4(1H)-ones by the reaction of either 1-substituted or 1,3-disubstituted 2-pyrazolin-5-ones with different o-halopyridinecarbonyl chlorides or with 3-chloroquinoline-2-car
Novel Extension of Meyers' Methodology: Stereoselective Construction of Axially Chiral 7,5-Fused Bicyclic Lactams
Penhoat, Mael,Levacher, Vincent,Dupas, Georges
, p. 9517 - 9520 (2007/10/03)
A novel extension of Meyer's lactamization is reported for the preparation of seven-membered ring lactams 1a-d incorporating a biaryl unit. The required keto-esters 2a-c were readily accessible via the Suzuki coupling reaction. A borylation-Suzuki couplin