1373038-00-6

Basic information

• Product Name: C₂₃H₂₄F₃NO₄
• Synonyms: C₂₃H₂₄F₃NO₄
• CAS NO: 1373038-00-6
• Molecular Weight: 435.443
• Mol File: 1373038-00-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₄F₃NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₄F₃NO₄(1373038-00-6)
• EPA Substance Registry System: C₂₃H₂₄F₃NO₄(1373038-00-6)

Safety Data

• Hazardous Substances Data: 1373038-00-6(Hazardous Substances Data)

Upstream product

• 51987-73-6 (S)-2-tert-butoxycarbonylamino-3-phenyl-propionic acid methyl ester 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 5139-89-9 4-phenoxybutyryl chloride 
• 168297-85-6 (S)-4-benzyl-5,5-dimethyloxazolidin-2-one 
• 63-91-2 L-phenylalanine 
• 6303-58-8 4-phenyloxybutanoic acid 
• 1373038-24-4 C₂₁H₂₄F₇NO₃ 
• 1373037-98-9 C₂₁H₂₆F₃NO₃ 
• 2314-97-8 iodotrifluoromethane 
• 1373037-74-1 (S)-4-benzyl-5,5-dimethyl-3-(4-phenoxybutanoyl)oxazolidin-2-one 
• 1373037-72-9 (S)-4-benzyl-3-(2-cyclohexylacetyl)-5,5-dimethyloxazolidin-2-one 
• 1207362-36-4 (S)-4-benzyl-3-hexanoyl-5,5-dimethyloxazolidin-2-one 

Relevant articles and documents

A simple method for asymmetric trifluoromethylation of N-acyl oxazolidinones via Ru-catalyzed radical addition to zirconium enolates

A Ru-catalyzed direct thermal trifluoromethylation and perfluoroalkylation of N-acyloxazolidinones has been developed. The reaction is experimentally simple and requires inexpensive reagents while providing good yields of products with good levels of stereocontrol. Preliminary studies have shown notable compatibility with functional groups, aromatics, and certain heteroaromatic substituents. The described method provides a useful alternative for the synthesis of fluorinated materials in an experimentally convenient manner.