1374035-95-6

Basic information

• Product Name: C₂₇H₃₂N₂O₂
• Synonyms: C₂₇H₃₂N₂O₂
• CAS NO: 1374035-95-6
• Molecular Weight: 416.563
• Mol File: 1374035-95-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₂N₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₂N₂O₂(1374035-95-6)
• EPA Substance Registry System: C₂₇H₃₂N₂O₂(1374035-95-6)

Safety Data

• Hazardous Substances Data: 1374035-95-6(Hazardous Substances Data)

Upstream product

• 80993-22-2 benzylmethylidenediphenylmethylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1374035-93-4 (R)-2-(benzhydrylamino)-3-phenylpropanenitrile 

Downstream Products

• 74822-65-4 (R)-(+)-1,2-diamino-3-phenylpropane dihydrochloride 

Relevant articles and documents

C2-symmetric recyclable organocatalyst for enantioselective Strecker reaction for the synthesis of α-amino acid and chiral diamine-an intermediate for APN inhibitor

Recyclable chiral amide-based organocatalyst 5 efficiently catalyzed asymmetric Strecker reaction of various aromatic and aliphatic N-benzhydrylimines with ethyl cyanoformate as cyanide source at -10 °C to give a high yield (95%) of α-aminonitriles with excellent chiral induction (ee, up to 99%) with the added advantage of recyclability. Based on experimental observations a probable mechanism was proposed for this reaction. This protocol with catalyst 5 was extended for the synthesis of (R)-phenylalanine and pharmaceutically important drug intermediate (R)-3-phenylpropane-1,2-diamine in high yield with high enantioselectivity.