1375257-29-6

Basic information

• Product Name: (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one
• Synonyms: (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one
• CAS NO: 1375257-29-6
• Molecular Weight: 232.326
• Mol File: 1375257-29-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one(1375257-29-6)
• EPA Substance Registry System: (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one(1375257-29-6)

Safety Data

• Hazardous Substances Data: 1375257-29-6(Hazardous Substances Data)

Upstream product

• 514214-80-3 [(S)-2-methyl-1-((S)-1-phenyl-ethylcarbamoyl)-propyl]-carbamic acid tert-butyl ester 
• 72-18-4 L-valine 
• 13734-41-3 t-Boc-L-valine 
• 1375257-37-6 (S)-3-[(R)-3-hydroxy-3-phenylpropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-32-1 (S)-3-[(S)-3-hydroxy-3-phenylpropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-24-1 N-acetyl-(S)-4-isopropyl-1-[(R)-1-phenylethyl] imidazolidin-2-one 
• 32315-10-9 bis(trichloromethyl) carbonate 
• 1375257-30-9 (S)-3-methyl-N₁-[(R)-1-phenylethyl]butane-1,2-diamine 
• 80650-85-7 (S)-2-amino-3-methyl-N-[(R)-1-phenylethyl]butanamide 

Downstream Products

• 1375257-32-1 (S)-3-[(S)-3-hydroxy-3-phenylpropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-39-8 (S)-3-[(S)-3-(4-fluorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-41-2 (S)-3-[(S)-3-(4-chlorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-43-4 (S)-3-[(S)-3-(2-chlorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-44-5 (S)-3-[(S)-3-(4-bromophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-45-6 (S)-3-[(S)-3-(4-methylphenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-46-7 (S)-3-[(S)-3-(2-methoxyphenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-47-8 (S)-3-[(S)-3-(furan-2-yl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-48-9 (S)-3-[(S)-3-hydroxy-3-(thiophen-2-yl)propanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-37-6 (S)-3-[(R)-3-hydroxy-3-phenylpropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-55-8 (S)-3-[(R)-3-(4-fluorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-56-9 (S)-3-[(R)-3-(4-chlorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-57-0 (S)-3-[(R)-3-(2-chlorophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 
• 1375257-58-1 (S)-3-[(R)-3-(4-bromophenyl)-3-hydroxypropanoyl]-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one 

Relevant articles and documents

Reversal of selectivity in acetate aldol reactions of N-acetyl-(S)-4- isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one

Synergistic effects of the exo- and endocyclic chiral centers of an imidazolidinone-based auxiliary were investigated in the perspective of acetate aldol reactions. The reversal in diastereoselectivity was accomplished by lithium and titanium enolate reactions, which proceed through proposed open and closed transitions states, respectively. The aldol adducts were used in the stereoselective synthesis of fluoxetine.