1375257-37-6Relevant articles and documents
Stereoselective synthesis of (S)-dapoxetine: A chiral auxiliary mediated approach
Khatik, Gopal L.,Sharma, Ratnesh,Kumar, Varun,Chouhan, Mangilal,Nair, Vipin A.
, p. 5991 - 5993 (2013/10/22)
An imidazolidin-2-one chiral auxiliary mediated acetate aldol reaction was explored in the enantioselective synthesis of (S)-dapoxetine (SSRI). The diastereoselective aldol adduct was transformed to highly enantiopure (S)-dapoxetine with overall good yield.