137868-52-1

Basic information

• Product Name: UDP-ALPHA-D-GALACTOSE DISODIUM SALT
• Synonyms: UDPG DISODIUM SALT;UDP-GALNAC, NA2;UDP-GAL DISODIUM SALT;UDP-GAL, NA2;UDP-GAL;UDP-GALACTOSE DISODIUM SALT;UDP-ALPHA-D-GALACTOSE DISODIUM SALT;URIDINE-DIPHOSPHATE-GALACTOSE DISODIUM SALT
• CAS NO: 137868-52-1
• Molecular Formula: C₁₅H₂₂N₂O₁₇P₂*2Na
• Molecular Weight: 610.27
• Mol File: 137868-52-1.mol
• Article Data: 1

Chemical Properties

• Flash Point: 27 °C
• Appearance: /
• Storage Temp.: −20°C
• Solubility: H2O: 50 mg/mL, clear, colorless
• Stability: Hygroscopic
• BRN: 5374254
• CAS DataBase Reference: UDP-ALPHA-D-GALACTOSE DISODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: UDP-ALPHA-D-GALACTOSE DISODIUM SALT(137868-52-1)
• EPA Substance Registry System: UDP-ALPHA-D-GALACTOSE DISODIUM SALT(137868-52-1)

Safety Data

• Hazard Codes: Xi,R
• Statements: 36/37/38-10
• Safety Statements: 26-16
• RIDADR: UN 2910 7
• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 137868-52-1(Hazardous Substances Data)

Usage

Description

UDP-ALPHA-D-GALACTOSE DISODIUM SALT, also known as Uridine 5′-diphospho-α-D-galactose or UDP-Gal, is an endogenous nucleotide sugar that serves as a donor substrate for galactosyltransferases. These enzymes are involved in the biosynthesis of galactose-containing oligosaccharides, which are essential components of various biological molecules. UDP-ALPHA-D-GALACTOSE DISODIUM SALT is a white powder and is a derivative of uridine.

Uses

Used in Enzyme Research:
UDP-ALPHA-D-GALACTOSE DISODIUM SALT is used as a gal transferase substrate for studying the activity and function of galactosyltransferases, which are crucial enzymes in the synthesis of complex carbohydrates.
Used in Synthesis of Inhibitors:
UDP-ALPHA-D-GALACTOSE DISODIUM SALT is used as a starting material in the synthesis of 5-CF3 UDP non-natural sugar nucleotides. These non-natural sugar nucleotides act as micromolar inhibitors of galactosyltransferases, which can be useful in the development of drugs targeting these enzymes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, UDP-ALPHA-D-GALACTOSE DISODIUM SALT is used as a key component in the development of drugs that target galactosyltransferases, potentially leading to treatments for various diseases related to carbohydrate metabolism and cell surface glycosylation.
Used in Biochemical Research:
UDP-ALPHA-D-GALACTOSE DISODIUM SALT is used as a research tool in biochemical studies to understand the role of galactose-containing oligosaccharides in cellular processes and their interactions with other biomolecules. This knowledge can contribute to the development of novel therapeutic strategies and diagnostic tools.

Biochem/physiol Actions

Uridine 5′-diphospho-α-D-galactose/UDP-Gal can block BALB/3T12 cell development. In mammals, it is very essential for glycoconjugate biosynthesis.

Upstream product

• 14795-21-2 galactose-α-1-phosphate barium salt 
• 1476-50-2 uridine 5'-triphosphate trisodium salt 

Downstream Products

• 208647-48-7 1-Naphthyl-α-D-glucopyranosid 
• 77171-31-4 2-phenylethyl-desulphoglucosinolate 
• 5115-75-3 desulfogalactotropaeolin 
• 5115-74-2 benzyl desulphoglucosinolate 
• 58-98-0 UDP 
• 2616-64-0 UDP-glucuronic acid 
• 1144040-14-1 4-nitrophenyl (β-D-galactopyranosyl)-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranoside 
• 1239315-18-4 4-nitrophenyl (β-D-glucopyranosyl)-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranoside 
• 116806-61-2 C₂₁H₃₁NO₁₁ 
• 3554-96-9 (2-acetamido-2-deoxy-3-O-β-D-galactopyranosyl-α-D-galactopyranosyl)-O-benzyl glycoside 
• 1239315-20-8 phenyl β-D-galactopyranosyl-(1->3)-2-acetamido-2-deoxy-β-D-galactopyranosyl-(1->4)-β-D-galactopyranosyl-(1->4)-1-thio-β-D-glucopyranoside 
• 1239315-21-9 C₃₈H₅₉NO₂₅S 
• 1239315-17-3 phenyl β-D-galactopyranosyl-(1->3)-(2-acetamido-2-deoxy-β-D-galactopyranosyl)-(1->4)-[5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonic acid-(2->3)]-β-D-galactopyranosyl-(1->4)-β-D-glucopyranoside 
• 105330-52-7 (+)-catechin 4'-O-β-D-glucopyranoside 

Relevant articles and documents

Practical enzyme-based syntheses of uridine 5'-diphosphogalactose and uridine 5'-diphospho-N-acetylgalactosamine on a gram scale

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