1378998-80-1

Basic information

• Product Name: 5-bromo-2-[(4-chlorophenyl)amino]pyrimidin-4(3H)-one
• CAS NO: 1378998-80-1
• Molecular Weight: 300.542
• Mol File: 1378998-80-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-bromo-2-[(4-chlorophenyl)amino]pyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-bromo-2-[(4-chlorophenyl)amino]pyrimidin-4(3H)-one(1378998-80-1)
• EPA Substance Registry System: 5-bromo-2-[(4-chlorophenyl)amino]pyrimidin-4(3H)-one(1378998-80-1)

Safety Data

• Hazardous Substances Data: 1378998-80-1(Hazardous Substances Data)

Upstream product

• 81560-03-4 2-methylsulfanyl-5-bromopyrimidin-4-one 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 1378998-84-5 5-bromo-4-chloro-N-(4-chlorophenyl)pyrimidin-2-amine 

Relevant articles and documents

SNAr reactions of 2-methylthio-4-pyrimidinones in pivalic acid: Access to functionalized pyrimidinones and pyrimidines

Pivalic acid is a useful medium to effect the direct SNAr displacement of 2-methylthio-4-pyrimidinones with a variety of anilines. Products are easily isolated in good to excellent yields, and following chlorination, provide an opportunity to r