1379511-99-5Relevant articles and documents
Palladium-catalyzed aerobic oxidative cyclization of N-aryl imines: Indole synthesis from anilines and ketones
Wei, Ye,Deb, Indubhusan,Yoshikai, Naohiko
supporting information; scheme or table, p. 9098 - 9101 (2012/07/14)
We report here an operationally simple, palladium-catalyzed cyclization reaction of N-aryl imines, affording indoles via the oxidative linkage of two C-H bonds under mild conditions using molecular oxygen as the sole oxidant. The process allows quick and atom-economical assembly of indole rings from inexpensive and readily available anilines and ketones and tolerates a broad range of functional groups.