138563-55-0

Basic information

• Product Name: Formamide, N-(3,4-difluorophenyl)- (9CI)
• Synonyms: Formamide, N-(3,4-difluorophenyl)- (9CI)
• CAS NO: 138563-55-0
• Molecular Formula: C₇H₅F₂NO
• Molecular Weight: 157.1175064
• Product Categories: HALIDE
• Mol File: 138563-55-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Formamide, N-(3,4-difluorophenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Formamide, N-(3,4-difluorophenyl)- (9CI)(138563-55-0)
• EPA Substance Registry System: Formamide, N-(3,4-difluorophenyl)- (9CI)(138563-55-0)

Safety Data

• Hazardous Substances Data: 138563-55-0(Hazardous Substances Data)

Upstream product

• 107-31-3 Methyl formate 
• 3863-11-4 3,4-difluoroaniline 

Downstream Products

• 472958-69-3 3,4-difluorophenyl isocyanide 
• 1026776-16-8 C₁₂H₈F₂N₂O 

Relevant articles and documents

Development of an Industrial Process Based on the Groebke-Blackburn-Bienaymé Multicomponent Reaction: Efficient Preparation- of 3-Aminoimidazo[1,2-a]pyrazines

3-Aminoimidazo[1,2-a]pyrazine is an important scaffold that is found in many drugs. This scaffold is rapidly accessible through a Groebke-Blackburn-Bienaymé cyclisation starting from an aminopyrazine, an aldehyde and an isocyanide. A scale-up process of this multicomponent reaction has been achieved in high yield and with excellent purity. The scope and limitations of this process leading to various 3-aminoimidazo[1,2-a]pyrazines are disclosed.