472958-69-3

Basic information

• Product Name: Benzene, 1,2-difluoro-4-isocyano- (9CI)
• Synonyms: Benzene, 1,2-difluoro-4-isocyano- (9CI);1,2-difluoro-4-isocyanobenzene
• CAS NO: 472958-69-3
• Molecular Formula: C7H3F2N
• Molecular Weight: 139.1022264
• Product Categories: HALIDE;ISONITRITE
• Mol File: 472958-69-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzene, 1,2-difluoro-4-isocyano- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2-difluoro-4-isocyano- (9CI)(472958-69-3)
• EPA Substance Registry System: Benzene, 1,2-difluoro-4-isocyano- (9CI)(472958-69-3)

Safety Data

• Hazardous Substances Data: 472958-69-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H3F2N/c1-10-5-2-3-6(8)7(9)4-5/h2-4H

Upstream product

• 3863-11-4 3,4-difluoroaniline 
• 138563-55-0 3,4-di-fluorophenyl formamide 

Relevant articles and documents

Development of an Industrial Process Based on the Groebke-Blackburn-Bienaymé Multicomponent Reaction: Efficient Preparation- of 3-Aminoimidazo[1,2-a]pyrazines

3-Aminoimidazo[1,2-a]pyrazine is an important scaffold that is found in many drugs. This scaffold is rapidly accessible through a Groebke-Blackburn-Bienaymé cyclisation starting from an aminopyrazine, an aldehyde and an isocyanide. A scale-up process of this multicomponent reaction has been achieved in high yield and with excellent purity. The scope and limitations of this process leading to various 3-aminoimidazo[1,2-a]pyrazines are disclosed.