138764-20-2

Basic information

• Product Name: 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile
• Synonyms: 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile;5-oxo-5,6,7,8-tetrahydronaphthalene-1-carbonitrile;1-NAPHTHALENECARBONITRILE, 5,6,7,8-TETRAHYDRO-5-OXO-;5-oxo-7,8-dihydro-6H-naphthalene-1-carbonitrile
• CAS NO: 138764-20-2
• Molecular Formula: C11H9NO
• Molecular Weight: 171.2
• Mol File: 138764-20-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile(138764-20-2)
• EPA Substance Registry System: 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile(138764-20-2)

Safety Data

• Hazardous Substances Data: 138764-20-2(Hazardous Substances Data)

Usage

General Description

5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile is a chemical compound with the molecular formula C13H9NO. It is a naphthalene derivative that contains a nitrile functional group. 5,6,7,8-tetrahydro-5-oxonaphthalene-1-carbonitrile is commonly used in organic synthesis and medicinal chemistry, where it serves as a building block for the synthesis of various pharmacologically active compounds. Its structure and reactivity make it a valuable intermediate in the production of pharmaceuticals and agrochemicals. Additionally, it has potential applications in the development of new materials and dyes. The compound's distinct structure and functional groups make it an important target for research in the field of organic chemistry.

Upstream product

• 68449-30-9 5-bromo-1-tetralone 
• 557-21-1 zinc(II) cyanide 
• 544-92-3 copper(I) cyanide 
• 930-68-7 cyclohexenone 
• 183489-42-1 5-(N,N-dimethylamino)-2,4-pentadienenitrile 

Downstream Products

• 1307230-08-5 (S)-N-(5-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)-3-hydroxyazetidine-1-carboxamide 
• 1307230-06-3 (S)-5-(3-(5-amino-5,6,7,8-tetrahydronaphthalen-1-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile 
• 1307230-87-0 (S)-tert-butyl (5-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamate 
• 1307230-03-0 (R)-5-(3-(5-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile 

Relevant articles and documents

Seco-B-ring steroidal dienynes with aromatic D ring: Design, synthesis and biological evaluation

Continuing our structure-activity studies on the vitamin D analogs with the altered intercyclic seco-B-ring fragment, we designed compounds possessing dienyne system conjugated with the benzene D ring. Analysis of the literature data and the docking exper

SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS AND METHODS OF CHIRAL SYNTHESIS

Compounds that selectively modulate the sphingosine 1 phosphate receptor are provided including compounds which modulate subtype 1 of the S1P receptor. Methods of chiral synthesis of such compounds is provided. Uses, methods of treatment or prevention and methods of preparing inventive compositions including inventive compounds are provided in connection with the treatment or prevention of diseases, malconditions, and disorders for which modulation of the sphingosine 1 phosphate receptor is medically indicated.

Novel angular benzophenazines: Dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents

A series of substituted angular benzophenazines were prepared using a new synthetic route via a novel regiocontrolled condensation of 1,2-naphthoquinones and 2,3-diaminobenzoic acids. The synthesis and biological activity of this new series of substituted