1390616-74-6Relevant articles and documents
Analgesic and antiinflammatory activity of derivatives of 2-aminobenzothiazole
Deodhar, Meenakshi N.,Dongre, Ashishkumar C.,Kudale, Sayali D.
, p. 2747 - 2752 (2012/09/22)
A series of 5-(4-substituted benzylidene-2-(substituted benzo[d]thiazol-2-ylimino)thiazolidin-4-one (5a-r) have been synthesized from 2-aminobenzothiazole as starting material. Condensation of thiazolidin-4-one with different substituted aromatic benzaldehyde occurred at reactive methylene group present at C-5 position of thiazolidin-4-one ring and resulted in the formation of compounds (5a-r). These were characterized using physical and spectral methods. The compounds (5a-r) were evaluated for analgesic and antiinflammatory activity using in vivo models.