1392827-19-8

Basic information

• Product Name: 6-chloro-N-phenethylhexanamide
• Synonyms: 6-chloro-N-phenethylhexanamide
• CAS NO: 1392827-19-8
• Molecular Weight: 253.772
• Mol File: 1392827-19-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-chloro-N-phenethylhexanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-N-phenethylhexanamide(1392827-19-8)
• EPA Substance Registry System: 6-chloro-N-phenethylhexanamide(1392827-19-8)

Safety Data

• Hazardous Substances Data: 1392827-19-8(Hazardous Substances Data)

Upstream product

• 10297-06-0 1-chloro-5-hexyne 
• 64-04-0 phenethylamine 
• 1370291-67-0 potassium 6-chlorohexanoyltrifluoroborate 
• 69424-54-0 O-benzoyl-N-phenethylhydroxylamine 

Relevant articles and documents

Ruthenium-Catalyzed Oxidative Amidation of Alkynes to Amides

Complex CpRuCl(PPh3)2 catalyzes reactions of terminal alkynes with 4-picoline N-oxide and primary and secondary amines to afford the corresponding amides. The reactions occur in chlorinated solvent and aqueous medium, showing applications in peptide chemistry. Stoichiometric studies reveal that the true catalysts of the processes are the vinylidene cations [CpRu(=C=CHR)(PPh3)2]+ which are oxidized to the Ru(η2-CO)-ketenes by the N-oxide. Finally, nucleophilic additions of primary and secondary amines to the free ketenes yield the corresponding amides.