69424-54-0

Basic information

• Product Name: Benzeneethanamine, N-(benzoyloxy)-
• CAS NO: 69424-54-0
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol File: 69424-54-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzeneethanamine, N-(benzoyloxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneethanamine, N-(benzoyloxy)-(69424-54-0)
• EPA Substance Registry System: Benzeneethanamine, N-(benzoyloxy)-(69424-54-0)

Safety Data

• Hazardous Substances Data: 69424-54-0(Hazardous Substances Data)

Upstream product

• 64-04-0 phenethylamine 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 126770-48-7 tert-butyl (S)-(1-oxo-1-(phenethylamino)-3-phenylpropan-2-yl)carbamate 
• 33799-96-1 N-(2-phenylethyl)-4-fluorobenzamide 
• 551908-65-7 4-fluoro-N-(3-phenylpropyl)-benzamide 
• 877-95-2 methyl-N-(benzyl-methyl)-formamide 
• 39887-24-6 N-(2-phenylethyl)-p-chlorobenzamide 
• 38925-77-8 4-methyl-N-(2-phenylethyl)benzamide 
• 3278-14-6 N-phenethylbenzamide 
• 83697-66-9 N-(2-phenylethyl)-4-phenylbutanamide 
• 560089-64-7 N-phenethylnonanamide 
• 959285-73-5 hex-5-enamide, N-(2-phenylethyl)- 
• 41431-75-8 N-phenethyl-2-phenylpropanamide 
• 83303-97-3 2-(4-methylphenyl)-N-phenethylacetamide 
• 1392827-19-8 6-chloro-N-phenethylhexanamide 
• 1392827-18-7 methyl (5-oxo-5-(phenethylamino)pentyl)carbamate 

Relevant articles and documents

Direct N-O bond formation via oxidation of amines with benzoyl peroxide

Herein, we report a general and efficient method for direct N-O bond formation without undesirable C-N bond (amide) formation starting from commercially available amines and benzoyl peroxide. The oxidation of 1,2-diamines to furnish bis-(benzoyloxy)-1,2-diamines is reported for the first time. We found that a significant amount of water (BPO?:?water = 3?:?1) in combination with Cs2CO3 is necessary to achieve high selectivity and yield. The reaction conditions are applicable to a wide range of 1,2-diamine and 1,2-disubstituted-1,2-diamine substrates. Additionally this method is highly applicable to primary and secondary amines. Further, the present method can access chiral bis-hydroxamic acids and bis-hydroxyl amines in just two steps from 1,2-diamines. The reaction conditions are simple, mild and inert atmosphere free. The synthetic potential of this methodology is further demonstrated in the short synthesis of a chiral BHA ligand.

Amide groups switch selectivity: C-H trifluoromethylation of α,β-unsaturated amides and subsequent asymmetric transformation

The first direct C-H β-trifluoromethylation of unsubstituted or α-alkyl-substituted α,β-unsaturated carbonyl compounds under metal-free conditions was realized with excellent regio- and stereoselectivity as well as a very broad substrate scope. Both olefi

Synthesis of secondary amines via N-(benzoyloxy)amines and organoboranes

A variety of primary amines (R-NH2) were converted to their corresponding N-(benzoyloxy)amines (i.e., R-NHOCOPh) under biphasic conditions in excellent yields (63-90%). The intermediate N- (benzoyloxy)amines were converted to their N-ethylamine derivatives upon reaction with triethylborane in THF in good yield (54-89%). These experiments demonstrated the similar chemistry of N-chloro- and N-(benzoyloxy)amines with organoboranes.