1393937-82-0

Basic information

• Product Name: 1-ethyl-6-fluoro-4-oxo-7-(4-(N-(phenylsulfonyl)carbamimidoyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
• CAS NO: 1393937-82-0
• Molecular Weight: 501.538
• Mol File: 1393937-82-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-ethyl-6-fluoro-4-oxo-7-(4-(N-(phenylsulfonyl)carbamimidoyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ethyl-6-fluoro-4-oxo-7-(4-(N-(phenylsulfonyl)carbamimidoyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid(1393937-82-0)
• EPA Substance Registry System: 1-ethyl-6-fluoro-4-oxo-7-(4-(N-(phenylsulfonyl)carbamimidoyl)piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid(1393937-82-0)

Safety Data

• Hazardous Substances Data: 1393937-82-0(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

Design, synthesis, biological evaluation, and molecular docking studies of quinolone derivatives as potential antitumor topoisomerase I inhibitors

A novel series of quinolone derivatives (6a-n) were designed and synthesized, and their biological activities were evaluated as potential antitumor topoisomerase I (Top I) inhibitors. Among these compounds, 6j exhibited the most potent antitumor activities against multiple cancer cell lines. Docking simulation was performed to insert compound 6j into the crystal structure of DNA-Top I to determine the probable binding model.