1394121-05-1 Usage
Chemical structure
The compound has a complex structure with a cyclohexane ring and a benzodiazole ring, with an ethynyl group attached to the benzodiazole ring.
Functional groups
It contains an aminopyrimidine group and a methoxyethylamino group.
Potential applications
Due to the presence of the benzodiazole and aminopyrimidine moieties, the compound may have potential pharmaceutical or biological applications.
Therapeutic activities
The benzodiazole and aminopyrimidine groups are associated with various therapeutic activities.
Further research
The specific characteristics and potential uses of this compound would need to be further explored through research and testing.
Synthesis
The synthesis of the compound is not described in the material provided, but it likely involves the formation of the cyclohexane ring, the benzodiazole ring, and the attachment of the ethynyl, aminopyrimidine, and methoxyethylamino groups.
Purity
The purity of the compound is not mentioned in the material provided, but it may be important for its potential applications and further research.
Check Digit Verification of cas no
The CAS Registry Mumber 1394121-05-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,4,1,2 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1394121-05:
(9*1)+(8*3)+(7*9)+(6*4)+(5*1)+(4*2)+(3*1)+(2*0)+(1*5)=141
141 % 10 = 1
So 1394121-05-1 is a valid CAS Registry Number.
1394121-05-1Relevant articles and documents
Back pocket flexibility provides group II p21-activated kinase (PAK) selectivity for type i 1/2 kinase inhibitors
Staben, Steven T.,Feng, Jianwen A.,Lyle, Karen,Belvin, Marcia,Boggs, Jason,Burch, Jason D.,Chua, Ching-Ching,Cui, Haifeng,Dipasquale, Antonio G.,Friedman, Lori S.,Heise, Christopher,Koeppen, Hartmut,Kotey, Adrian,Mintzer, Robert,Oh, Angela,Roberts, David Allen,Rouge, Lionel,Rudolph, Joachim,Tam, Christine,Wang, Weiru,Xiao, Yisong,Young, Amy,Zhang, Yamin,Hoeflich, Klaus P.
, p. 1033 - 1045 (2014/03/21)
Structure-based methods were used to design a potent and highly selective group II p21-activated kinase (PAK) inhibitor with a novel binding mode, compound 17. Hydrophobic interactions within a lipophilic pocket past the methionine gatekeeper of group II
6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR
-
, (2015/05/06)
The invention relates to novel compounds of Formula I: wherein A, Y, R1, R2 and the subscript b each has the meaning as described herein and compounds of Formula I, and stereoisomers, geometric isomers, tautomers, solvates, metabolites, isotopes, pharmaceutically acceptable salts, or prodrugs thereof. Compounds of Formula I and pharmaceutical compositions thereof are useful in the treatment of disease and disorders in which undesired or over-activation of NF-kB signaling is observed.
