139557-97-4

Basic information

• Product Name: 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester
• CAS NO: 139557-97-4
• Molecular Weight: 486.347
• Mol File: 139557-97-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester(139557-97-4)
• EPA Substance Registry System: 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester(139557-97-4)

Safety Data

• Hazardous Substances Data: 139557-97-4(Hazardous Substances Data)

Upstream product

• 139557-94-1 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid methyl ester 
• 114506-09-1 3-(1-Methyl-2-oxo-5-vinyl-cyclopentyl)-propionic acid methyl ester 
• 58860-00-7 methyl 3-(5-oxocyclopent-1-enyl)propanoate 
• 6971-51-3 3-methoxybenzyl alcohol 
• 139557-96-3 (2-iodo-5-methoxyphenyl)methanol 
• 139557-97-4 3-((6R,7R)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester 
• 139557-94-1 3-((6R,7S)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid methyl ester 

Downstream Products

• 139557-96-3 (2-iodo-5-methoxyphenyl)methanol 
• 1091-94-7 (+/-)-oestrone methyl ester 
• 1238-31-9 C₂₁H₂₈O₃ 
• 139557-97-4 3-((6R,7S)-6-Methyl-7-vinyl-1,4-dioxa-spiro[4.4]non-6-yl)-propionic acid 2-iodo-5-methoxy-benzyl ester 
• 6971-51-3 3-methoxybenzyl alcohol 
• 139557-99-6 C₂₁H₂₆O₄ 

Relevant articles and documents

Anionic Fries Rearrangements of Esters of ortho-Iodobenzyl Alcohols: Rapid Routes to Oestrone Methyl Ether and Its 9β Epimer, and Aryl Naphthalide Lignans

A fast, general, low-temperature rearrangement of ortho-iodobenzyl esters, triggered by lithium-iodine exchange, leads to isobenzofurans which are intercepted in situ by inter and intramolecular Diels-Alder (IMDA) reactions to produce a variety of carbocycles including natural lignans and steroids.