13961-95-0

Basic information

• Product Name: Bis-N-benzyloxycarbonyl cystine di p-nitrophenyl ester
• Synonyms: Bis-N-benzyloxycarbonyl cystine di p-nitrophenyl ester
• CAS NO: 13961-95-0
• Molecular Weight: 750.764
• Mol File: 13961-95-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Bis-N-benzyloxycarbonyl cystine di p-nitrophenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Bis-N-benzyloxycarbonyl cystine di p-nitrophenyl ester(13961-95-0)
• EPA Substance Registry System: Bis-N-benzyloxycarbonyl cystine di p-nitrophenyl ester(13961-95-0)

Safety Data

• Hazardous Substances Data: 13961-95-0(Hazardous Substances Data)

Upstream product

• 501-53-1 benzyl chloroformate 
• 56-89-3 L-cystine 
• 100-02-7 4-nitro-phenol 
• 6968-11-2 N,N'-bis(benzyloxycarbonyl)-L-cystine 

Downstream Products

• 137197-01-4 S(β-Cyanoethyl)-Z-cysteinyl histidine methyl ester 
• 93679-30-2 N-Z-Cysteinyl histidine methyl ester 
• 17607-25-9 Bis-N-benzyloxycarbonyl cystinyl di-histidine methyl ester 
• 13961-96-1 (Z-Cys-NH₂)2 
• 24948-53-6 N-glycine methyl ester disulfide 

Relevant articles and documents

Synthesis of " zinc finger " template

The zinc finger template brings about protein-DNA recognition. The first synthesis of a metal template which incorporates the essential features of the zinc finger motif and represented by structure (a) has been achieved from the key tripeptide bis-N-benzyloxycarbonyl cystinyl di-histidine methyl ester (2) using a novel thiol-disulfide exchange and subsequent complexation. The cobalt motif (5) has been similarly prepared. FAB mass spectrum 1D nmr COSY and NOESY spectra, difference NOe of (1) and the UV of (5) are in very good agreement with a ligand distribution profile around the central tetrahedral metal ion similar to that deduced for natural and synthetic zinc finger proteins. The potential of (1) or its appropriate variants in the understanding of diverse facets of DNA recognition is discussed.