1398507-09-9 Usage
Description
4-((4-amino-5-bromo-6-chloropyrimidin-2-yl)amino)benzonitrile is a chemical compound characterized by its unique molecular structure, featuring a benzonitrile core with a pyrimidinylamine group attached. 4-((4-amino-5-bromo-6-chloropyrimidin-2-yl)amino)benzonitrile is known for its specific properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
4-((4-amino-5-bromo-6-chloropyrimidin-2-yl)amino)benzonitrile is used as an impurity in the production of Etravirine (E937000), a novel HIV reverse transcriptase inhibitor. 4-((4-amino-5-bromo-6-chloropyrimidin-2-yl)amino)benzonitrile plays a significant role in the treatment of HIV infection by contributing to the development and effectiveness of the drug.
Application Reason:
The presence of 4-((4-amino-5-bromo-6-chloropyrimidin-2-yl)amino)benzonitrile in Etravirine is crucial for its function as an HIV reverse transcriptase inhibitor. It helps in the development of a potent drug that can effectively combat the virus and improve the quality of life for patients suffering from HIV infection.
Check Digit Verification of cas no
The CAS Registry Mumber 1398507-09-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,8,5,0 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1398507-09:
(9*1)+(8*3)+(7*9)+(6*8)+(5*5)+(4*0)+(3*7)+(2*0)+(1*9)=199
199 % 10 = 9
So 1398507-09-9 is a valid CAS Registry Number.
1398507-09-9Relevant articles and documents
Process for the Synthesis of Etravirine and Its Intermediates
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, (2015/12/05)
The invention discloses the synthesis of Etravirine via intermediate 4-((4-amino-5-bromo-6-chloropyrimidin-2-yl) amino)benzonitrile and process for the preparation of Etravirine of the formula-I.
