1401299-04-4Relevant articles and documents
Photochemical studies on acyclic alkyl aromatic ketones in the solid state: Asymmetric induction and increased chemoselectivity
Ma, Manling,Feng, Wei,Guo, Fang,Yang, Chao,Xia, Wujiong
, p. 8875 - 8879 (2012/10/29)
The acyclic alkyl aromatic ketones, 2-isobutyl-4-methyl-1-arylpentan-1-one derivatives were designed and synthesized for photochemical investigations. Irradiation of such compounds in acetonitrile solution led to the Yang cyclization and Norrish type II cleavage photoproducts with a ratio of 1:1, whereas the reaction conducted in the solid state using the ionic chiral auxiliary method led to only the Yang cyclization product with as high as 99% ee. Furthermore, the conformational transitions were first observed in the reaction.
