140146-13-0

Basic information

• Product Name: Propanoic acid, 2-(2-chlorophenoxy)-, methyl ester, (R)-
• CAS NO: 140146-13-0
• Molecular Formula: C10H11ClO3
• Molecular Weight: 214.649
• Mol File: 140146-13-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-(2-chlorophenoxy)-, methyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-(2-chlorophenoxy)-, methyl ester, (R)-(140146-13-0)
• EPA Substance Registry System: Propanoic acid, 2-(2-chlorophenoxy)-, methyl ester, (R)-(140146-13-0)

Safety Data

• Hazardous Substances Data: 140146-13-0(Hazardous Substances Data)

Upstream product

• 211184-89-3 2-(2-chloro-phenoxy)-propionyl chloride 
• 76466-16-5 2-(2-chlorophenoxy)propionic acid 
• 74411-15-7 2-(2-chlorophenoxy)propanoic acid methyl ester 
• 20047-41-0 methyl (2S)-2-bromopropanoate 
• 3046-25-1 o-chlorophenol, potassium salt 
• 5445-17-0 Methyl 2-bromopropionate 
• 95-57-8 2-monochlorophenol 
• 67-56-1 methanol 

Downstream Products

• 76466-16-5 2-(2-chlorophenoxy)propionic acid 
• 25140-86-7 (R)-2-(2-chlorophenoxy) propanoic acid 
• 25140-86-7 (S)-2-(2-chlorophenoxy) propanoic acid 
• 122674-93-5 (S)-methyl 2-(2-chlorophenoxy) propionate 

Relevant articles and documents

Might the observed α2A-adrenoreceptor agonism or antagonism of allyphenyline analogues be ascribed to different molecular conformations?

We recently reported that the α2-adrenoreceptor (AR) ligand allyphenyline (9) significantly enhanced morphine analgesia (due to its α2C-AR agonism), was devoid of sedative side effects (due to its α2A-AR antagonism), preve

Enzyme catalysed hydrolysis of chlorophenoxypropionates

We report on the enzymatic hydrolysis of methyl 2-phenoxypropionate and of the following chlorinated derivatives: methyl o-chloro-, m-chloro-, p-chloro-, and o,p-dichloro-2-phenoxypropionates. α-Chymotripsyn, lipase, and pig liver esterase have an R enantioselectivity whereas subtilisin has an S enantioselectivity.Enantiomeric excess (e.e.) cover a wide range (from 5 to 100percent).