1402081-42-8

Basic information

• Product Name: (R)-3-methyl-N¹,N⁶-diphenylhexanediamide
• CAS NO: 1402081-42-8
• Molecular Weight: 310.396
• Mol File: 1402081-42-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (R)-3-methyl-N¹,N⁶-diphenylhexanediamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-methyl-N¹,N⁶-diphenylhexanediamide(1402081-42-8)
• EPA Substance Registry System: (R)-3-methyl-N¹,N⁶-diphenylhexanediamide(1402081-42-8)

Safety Data

• Hazardous Substances Data: 1402081-42-8(Hazardous Substances Data)

Upstream product

• 623-82-5 (R)-3-methylhexanedioic acid 
• 62-53-3 aniline 

Relevant articles and documents

Erratum: Enantioselective baeyer-villiger oxidation: Desymmetrization of meso cyclic ketones and kinetic resolution of racemic 2-arylcyclohexanones (Journal of the American Chemical Society (2012) 134 (17023-17026) DOI:10.1021/ja309262f)

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Enantioselective baeyer-villiger oxidation: Desymmetrization of meso cyclic ketones and kinetic resolution of racemic 2-arylcyclohexanones

Catalytic enantioselective Baeyer-Villiger (BV) oxidations of racemic and meso cyclic ketones were achieved in the presence of chiral N,N'-dioxide-Sc III complex catalysts. The BV oxidations of prochiral cyclohexanones and cyclobutanones afforded series of optically active μ- and γ-lactones, respectively, in up to 99% yield and 95% ee. Meanwhile, the kinetic resolution of racemic 2-arylcyclohexanones was also realized via an abnormal BV oxidation. Enantioenriched 3-aryloxepan-2-ones, whose formation is counter to the migratory aptitude, were obtained preferentially. Both the lactones and the unreacted ketones were obtained with high ee values.