1403893-61-7

Basic information

• Product Name: 4-chloro-5-fluoro-6-vinylpyriMidine
• Synonyms: 4-chloro-5-fluoro-6-vinylpyriMidine
• CAS NO: 1403893-61-7
• Molecular Formula: C6H4ClFN2
• Molecular Weight: 158.5607632
• Mol File: 1403893-61-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 233.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.343±0.06 g/cm3(Predicted)
• Vapor Pressure: 1.04-1.733hPa at 20-25℃
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: -1.39±0.26(Predicted)
• CAS DataBase Reference: 4-chloro-5-fluoro-6-vinylpyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-5-fluoro-6-vinylpyriMidine(1403893-61-7)
• EPA Substance Registry System: 4-chloro-5-fluoro-6-vinylpyriMidine(1403893-61-7)

Safety Data

• Hazardous Substances Data: 1403893-61-7(Hazardous Substances Data)

Upstream product

• 62393-52-6 N-isopropyl-N-methylenepropan-2-aminium chloride 
• 898044-55-8 4-chloro-5-fluoro-6-methylpyrimidine 
• 213265-83-9 4,6-dichloro-5-fluoropyrimidine 
• 7486-35-3 tri-n-butyl(vinyl)tin 

Downstream Products

• 1602485-94-8 (2R,3S)-1-chloro-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)butan-2-ol 
• 188416-38-8 (2R,3S)-3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1 yl)butan-2-ol 
• 137234-63-0 (2S,3R)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF VORICONAZOLE AND ANALOGUES THEREOF

The present invention provides a process for preparing a compound of formula: (Formula XI and XII) (XI) (XII) wherein X, Y, Z, A, B and E are as defined herein, by reacting a compound of formula: (Formula XIII) (XIII) with a compound of formula: (Formula XIV and XV) (XIV) (XV) respectively, in the presence of a transition metal catalyst, a ligand suitable for use with 15 the catalyst and a reducing agent. The invention also provides novel intermediates.