1408168-69-3 Usage
Description
Potassium (2-Methoxyethyl)trifluoroborate is a chemical compound that is utilized in the field of organic synthesis. It is known for its ability to facilitate the formation of aryl/heteroarylethyloxy motifs, which are essential structural elements in various organic molecules and pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
Potassium (2-Methoxyethyl)trifluoroborate is used as a synthetic reagent for the creation of aryl/heteroarylethyloxy motifs through Suzuki-Miyaura Cross-Coupling. This application is crucial in the development of new pharmaceutical compounds, as these motifs are often found in active drug molecules, contributing to their biological activity and therapeutic effects.
Used in Chemical Research:
In the field of chemical research, Potassium (2-Methoxyethyl)trifluoroborate serves as a valuable tool for the synthesis of complex organic molecules. Its ability to facilitate the formation of aryl/heteroarylethyloxy motifs makes it an essential component in the development of novel chemical entities with potential applications in various industries, including materials science, agrochemistry, and environmental science.
Used in Material Science:
Potassium (2-Methoxyethyl)trifluoroborate is also used in the synthesis of advanced materials with unique properties. The aryl/heteroarylethyloxy motifs created using this compound can be incorporated into the structures of polymers, nanoparticles, and other materials, leading to the development of innovative products with enhanced performance characteristics.
Check Digit Verification of cas no
The CAS Registry Mumber 1408168-69-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,8,1,6 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1408168-69:
(9*1)+(8*4)+(7*0)+(6*8)+(5*1)+(4*6)+(3*8)+(2*6)+(1*9)=163
163 % 10 = 3
So 1408168-69-3 is a valid CAS Registry Number.
1408168-69-3Relevant articles and documents
Suzuki-Miyaura cross-coupling of potassium alkoxyethyltrifluoroborates: Access to aryl/heteroarylethyloxy motifs
Fleury-Bregeot, Nicolas,Presset, Marc,Beaumard, Floriane,Colombel, Virginie,Oehlrich, Daniel,Rombouts, Frederik,Molander, Gary A.
, p. 10399 - 10408 (2013/01/15)
The introduction of an alkoxyethyl moiety onto aromatic substructures has remained a long-standing challenge for synthetic organic chemists. The main reasons are the inherent instability of alkoxyethylmetallic species and the lack of general procedures to access them. A new method utilizing a cross-coupling strategy based on the exceptional properties of organotrifluoroborates has been developed, and the method allows an easy and efficient installation of this unit on a broad range of aryl and heteroaryl bromides.
