80314-58-5

Basic information

• Product Name: p-(2-methoxyethyl)anisole
• Synonyms: p-(2-methoxyethyl)anisole;Benzene, 1-methoxy-4-(2-methoxyethyl)-;1-Methoxy-4-(2-methoxyethyl)benzene;Methyl(4-methoxyphenethyl) ether;Einecs 279-449-1
• CAS NO: 80314-58-5
• Molecular Formula: C₁₀H₁₄O₂
• Molecular Weight: 166.21696
• EINECS: 279-449-1
• Mol File: 80314-58-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 223.4°C at 760 mmHg
• Flash Point: 77°C
• Appearance: /
• Density: 0.982g/cm³
• Vapor Pressure: 0.144mmHg at 25°C
• Refractive Index: 1.489
• CAS DataBase Reference: p-(2-methoxyethyl)anisole(CAS DataBase Reference)
• NIST Chemistry Reference: p-(2-methoxyethyl)anisole(80314-58-5)
• EPA Substance Registry System: p-(2-methoxyethyl)anisole(80314-58-5)

Safety Data

• Hazardous Substances Data: 80314-58-5(Hazardous Substances Data)

Usage

Description

p-(2-methoxyethyl)anisole, also known as p-methoxyphenethyl methyl ether, is an organic compound that serves as a valuable synthetic intermediate in chemical synthesis. It is characterized by the presence of a methoxyethyl group attached to an anisole moiety, which contributes to its unique chemical properties and reactivity.

Uses

Used in Chemical Synthesis:
p-(2-methoxyethyl)anisole is used as a synthetic intermediate for the preparation of various organic compounds. Its versatile structure allows it to be a key component in the synthesis of a wide range of molecules, making it an important reagent in organic chemistry.
Used in the Preparation of Terminal Alkenes:
p-(2-methoxyethyl)anisole is used as a reagent in the synthesis of terminal alkenes through Indium(I)-catalyzed alkyl-allyl coupling of Me ethers with 9-BBN-derived allylborane. This reaction provides a convenient method for the preparation of terminal alkenes, which are valuable building blocks in organic synthesis.
Used in the Synthesis of Hordenine (H669600):
p-(2-methoxyethyl)anisole is also utilized in the synthesis of hordenine (H669600), a compound with potential applications in various fields. Its involvement in the synthesis of hordenine highlights its importance as a synthetic intermediate in the preparation of biologically active molecules.

InChI:InChI=1/C10H14O2/c1-11-8-7-9-3-5-10(12-2)6-4-9/h3-6H,7-8H2,1-2H3

Upstream product

• 64304-83-2 trans-1-(4-methoxyphenyl)-2-methoxyethene 
• 67-56-1 methanol 
• 74-85-1 ethene 
• 877-68-9 4-trimethylsilylanisole 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 74-88-4 methyl iodide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 64-17-5 ethanol 
• 1796-64-1 4-methoxyphenethyl methyl carbonate 
• 702-23-8 2-(4-Methoxyphenyl)ethanol 
• 616-38-6 carbonic acid dimethyl ester 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 1408168-69-3 potassium trifluoro(2-methoxyethyl)-λ⁴-borate 
• 13139-86-1 4-methoxyphenyl magnesium bromide 

Downstream Products

• 14140-15-9 4-(2-bromoethyl)phenol 
• 80314-64-3 2-(chloromethyl)-1-methoxy-4-(2-methoxyethyl)benzene 
• 147159-76-0 2-methoxy-1-(4-methoxyphenyl)ethan-1-ol 
• 123-11-5 4-methoxy-benzaldehyde 
• 201039-53-4 1-Methoxy-4-(2-methoxy-1-nitrooxy-ethyl)-benzene 
• 80314-59-6 <2'-methoxy-5'-(2''-methoxyethyl)phenyl>acetonitrile 
• 80314-60-9 2-[2-Methoxy-5-(2-methoxy-ethyl)-phenyl]-3-oxo-butyronitrile 
• 56718-71-9 4-(2-methoxyethyl)phenol 
• 637-69-4 4-Methoxystyrene 
• 51125-16-7 5-(4-methoxyphenyl)-1-pentene 
• 104706-30-1 1-methoxy-4-(2'-methoxyethyl)cyclohexa-1,4-diene 

Relevant articles and documents

Copolymerization of carbon dioxide and propylene oxide by several metallosalen-based bifunctional catalysts

A series of new metallosalen-based bifunctional catalysts with Co(III), Cr(III), Fe(III), Mn(III), and Ni(III) were synthesized for the first time, and a detailed study on the mechanism of the copolymerization of CO2 and propylene oxide (PO) was performed. Meanwhile, the impact factors of the reaction conditions (metal cations, temperature, CO2 pressure, and reaction time) on catalytic activity and selectivity were investigated. The results indicated that, with the increase of temperature, both the catalyst efficiency and the molecular weight of the copolymer decrease for all the five complexes. The salen-Co(III) complex demonstrated higher activity under mild conditions: reaction temperature at 30 °C, copolymerization time of 24 hr, and 2 MPa of CO2 pressure. The DSC curve indicated that the PPC by the salen-Co(III) complex has the highest Tg of 46.19 °C. DTGA curves demonstrated that there were two thermal degradation peaks: the first is for the ester bond, and the second is for the C?C bond.

Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation

Under the conditions of oxidative gold catalysis, exposure of ethylene to aryl silanes and alcohols generates products of 1,2-oxyarylation. This provides a rare example of a process that allows catalytic differential 1,2-difunctionalization of this feedstock chemical.

Cross-coupling of alkyl halides with aryl or alkyl Grignards catalyzed by dinuclear Ni(ii) complexes containing functionalized tripodal amine-pyrazolyl ligands

Structurally distinctive dinuclear Ni(ii) complexes with furan or thiophene tethered amine-pyrazolyl tripodal hybrid ligands have been synthesized and crystallographically characterized. All complexes are catalytically active towards cross-coupling of aryl/alkyl Grignard reagents with β-H containing alkyl halides at room temperature in the presence of N,N,N',N'- tetramethylethylenediamine (TMEDA). The catalytic efficacy of the complexes is dependent on the tether substituent at the central amine. Two species, Ni(ii) TMEDA and Mg(ii) TMEDA complexes, have been isolated from the catalytic reaction mixtures under different conditions. Some ligand-stabilized Ni(ii) and Mg(ii) bimetallic species have also been identified in the ESI-MS spectra.