1414365-79-9Relevant articles and documents
Electrochemical HI-mediated Intermolecular C-N Bond Formation to Synthesize Imidazoles from Aryl Ketones and Benzylamines
Yang, Zan,Zhang, Jiaqi,Hu, Liping,Li, An,Li, Lijun,Liu, Kun,Yang, Tao,Zhou, Congshan
, p. 5952 - 5958 (2020/05/22)
An efficient and novel electrochemical oxidative tandem cyclization of aryl ketones and benzylamines for the synthesis of 1,2,4-trisubstituted-(1H)-imidazoles has been developed under metal- and oxidant-free conditions. This direct C-N bond formation strategy, with a broad functional group tolerance, affords the desired imidazoles in moderate to excellent yields.
Construction of substituted imidazoles from aryl methyl ketones and benzylamines via N-heterocyclic carbene-catalysis
Alanthadka, Anitha,Elango, Sankari Devi,Thangavel, Pavithra,Subbiah, Nagarajan,Vellaisamy, Sridharan,Chockalingam, Uma Maheswari
, p. 26 - 31 (2019/03/26)
A novel synthetic strategy for the construction of substituted imidazoles from acetophenones and benzylamines via N-heterocyclic carbene (NHC) - catalysis was reported. This reaction can be performed under solvent-free condition without pre-functionalization of substrates. Various substituted acetophenones and benzylamines were converted to its corresponding imidazoles with good to excellent yields.
I2-catalyzed synthesis of substituted imidazoles from vinyl azides and benzylamines
Xiang, Likui,Niu, Yanning,Pang, Xiaobo,Yang, Xiaodong,Yan, Rulong
, p. 6598 - 6600 (2015/04/14)
A novel and efficient I2-catalyzed oxidative tandem cyclization of simple vinyl azides and benzylamines has been developed for the synthesis of substituted imidazoles. In this reaction, various substituted groups on vinyl azides and benzylamines proceed smoothly and the desired imidazoles are obtained in moderate to good yields.
