1415-78-7

Basic information

• Product Name: solasodine-3β-acetate
• CAS NO: 1415-78-7
• Molecular Weight: 455.681
• Mol File: 1415-78-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: solasodine-3β-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: solasodine-3β-acetate(1415-78-7)
• EPA Substance Registry System: solasodine-3β-acetate(1415-78-7)

Safety Data

• Hazardous Substances Data: 1415-78-7(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 126-17-0 solasodine 
• 64-19-7 acetic acid 
• 19121-58-5 solasonine 
• 1000612-51-0 C₂₉H₄₃N₃O₃ 
• 1061-54-7 diosgenin acetate 

Downstream Products

• 126-17-0 solasodine 
• 4860-15-5 solasodine N,O-diacetate 
• 979-02-2 16-dehydropregnenolone acetate 

Relevant articles and documents

Facile synthesis of solasodine based on a mild halogenation-ring opening reaction of spiroketals in steroidal sapogenins

Herein we report a halogenation-ring opening reaction of spiroketals in steroidal sapogenins at room temperature to gain highly valuable ω-halo enol ethers in excellent yields. Boosted by this method, we have prepared solasodine, an antitumor steroidal alkaloid, from diosgenin acetate in three steps with an overall yield of 50%.

Application of hypoiodite-mediated aminyl radical cyclization to synthesis of solasodine acetate

Solasodine acetate, an anticancer steroidal alkaloid, was synthesized from diosgenin in 8 steps with an overall yield of 23%. A key synthetic step involves the formation of 5/6-oxazaspiroketal moiety via hypoiodite-mediated aminyl radical cyclization of a steroidal primary amine.