1415234-13-7Relevant articles and documents
Cytotoxic 2-phenyacrylnitriles, the importance of the cyanide moiety and discovery of potent broad spectrum cytotoxic agents
Tarleton, Mark,Gilbert, Jayne,Sakoff, Jennette A.,McCluskey, Adam
, p. 65 - 73 (2013/01/15)
We previously reported the discovery of a simple conjugated cyano pharmacophore which had led to the development of (Z)-2-(3,4-dichlorophenyl)-3- (4-nitrophenyl)acrylonitrile (1), as a selective inhibitor of oestrogen receptor positive (ER+ve) human breas