1415814-28-6

Basic information

• Product Name: H-Asp(DEACE)-D-Phe-Lys(Boc)-Gly-OH
• CAS NO: 1415814-28-6
• Molecular Weight: 808.929
• Mol File: 1415814-28-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: H-Asp(DEACE)-D-Phe-Lys(Boc)-Gly-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-Asp(DEACE)-D-Phe-Lys(Boc)-Gly-OH(1415814-28-6)
• EPA Substance Registry System: H-Asp(DEACE)-D-Phe-Lys(Boc)-Gly-OH(1415814-28-6)

Safety Data

• Hazardous Substances Data: 1415814-28-6(Hazardous Substances Data)

Upstream product

• 54711-39-6 7-(diethylamino)-2-oxo-2H-1-benzopyran-4-carboxaldehyde 
• 91-44-1 7-diethylamino-4-methylcoumarin 
• 1415814-22-0 7-(N,N-diethylamino)-4-(1'-hydroxyeth-1'-yl)coumarin 
• 29022-11-5 N-(fluoren-9-ylmethoxycarbonyl)glycine 
• 1415814-26-4 Fmoc-Asp(DEACE)-OH 
• 71989-26-9 Fmoc-Lys(tert-butoxycarbonyl) 
• 86123-10-6 Fmoc-D-Phe-OH 
• 1415814-24-2 C₃₈H₄₂N₂O₈ 

Relevant articles and documents

Ethyl substituted coumarin-4-yl derivatives as photoremovable protecting groups for amino acids with improved stability for SPPS

The synthesis, photochemical properties and chemical stability of 7-(N,N-diethylamino-coumarin-4-yl)-1-ethyl (DEACE) photoremovable protecting group for carboxylic acids are presented. We demonstrate that the ethyl substituent of DEACE improves the hydrolytic stability of the protected ester in basic conditions used in solid phase peptide synthesis (SPPS) and retains the good photochemical properties of the coumarin-4-yl methyl derivatives. DEACE allows the preparation of peptides with protected carboxylic side groups with high yield via SPPS.