1416422-98-4Relevant articles and documents
Facile preparation of highly-functionalized, nitrogen-bearing diarylmethanes
Schmink, Jason R.,Tudge, Matthew T.
, p. 15 - 20 (2013/02/21)
A palladium-catalyzed cross coupling of nitrogen bearing heterocyclic chloromethyl derivatives with aryl and heteroaryl boronic acids has been developed. In almost all cases, highly efficient cross-couplings were observed at ambient temperature, mitigating unwanted thermally induced side-reactions. The comprehensive substrate scope and respectable yields highlight the synthetic utility of this reaction.