1417611-78-9

Basic information

• Product Name: (S)-t-butyl 2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)propanoate
• Synonyms: (S)-t-butyl 2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)propanoate
• CAS NO: 1417611-78-9
• Molecular Weight: 424.543
• Mol File: 1417611-78-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-t-butyl 2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-t-butyl 2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)propanoate(1417611-78-9)
• EPA Substance Registry System: (S)-t-butyl 2-(diphenylmethyleneamino)-3-(1H-indol-3-yl)propanoate(1417611-78-9)

Safety Data

• Hazardous Substances Data: 1417611-78-9(Hazardous Substances Data)

Upstream product

• 81477-94-3 N-(diphenylmethylene)glycine tert-butyl ester 
• 87-52-5 3-(Dimethylaminomethyl)indole 
• 16620-52-3 5-methoxygramine 

Relevant articles and documents

One-pot enantioselective synthesis of tryptophan derivatives via phase-transfer catalytic alkylation of glycine using a cinchona-derived catalyst

Tryptophans are building blocks for many natural products. This paper describes the enantiospecific synthesis of ring-A substituted tryptophan derivatives from commercially available gramines using chiral phase-transfer conditions. This one-pot reaction avoids protecting/deprotecting the indolylic nitrogen of gramine by choosing a chemoselective quaternization reagent, 4-(trifluoro-methoxy)benzyl bromide, to produce an electrophilic salt intermediate, which is subsequently alkylated in good yield with high enantiomeric excess. Georg Thieme Verlag KG Stuttgart · New York.