1418003-58-3

Basic information

• Product Name: 3-{2-[2-(morpholin-4-yl)ethoxy]ethyl}-5,5-diphenylimidazolidine-2,4-dione
• Synonyms: 3-{2-[2-(morpholin-4-yl)ethoxy]ethyl}-5,5-diphenylimidazolidine-2,4-dione
• CAS NO: 1418003-58-3
• Molecular Weight: 409.485
• Mol File: 1418003-58-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{2-[2-(morpholin-4-yl)ethoxy]ethyl}-5,5-diphenylimidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{2-[2-(morpholin-4-yl)ethoxy]ethyl}-5,5-diphenylimidazolidine-2,4-dione(1418003-58-3)
• EPA Substance Registry System: 3-{2-[2-(morpholin-4-yl)ethoxy]ethyl}-5,5-diphenylimidazolidine-2,4-dione(1418003-58-3)

Safety Data

• Hazardous Substances Data: 1418003-58-3(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 1418003-55-0 2-[2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)ethoxy]ethyl-4-methylbenzenesulphonate 
• 19249-03-7 triethylene glycol di-(p-toluenesulfonate) 
• 630-93-3 sodium phenytoin 

Relevant articles and documents

Phenytoin-based bivalent ligands: Design, synthesis and anticonvulsant activity

Synthesis, characterization and anticonvulsant properties of new bivalent ligands derived from phenytoin were described. Initial anticonvulsant screening was performed using maximal electroshock (MES) and pentylenetetrazole (PTZ) screens in mice. The neurotoxicity for compounds that showed significant anticonvulsant activity was determined applying the rotorod test. Most of the test compounds were found to be effective in at least one seizure model in a dose of 100 mg/kg. Compound 5e exhibited marked anticonvulsant activity in both MES and PTZ screens. The computer-aided prediction of biological activity was carried out.