1420041-65-1

Basic information

• Product Name: 1,3-bis(4-fluorophenyl)propyl-2-yn-1-one
• Synonyms: 1,3-bis(4-fluorophenyl)propyl-2-yn-1-one
• CAS NO: 1420041-65-1
• Molecular Weight: 242.225
• Mol File: 1420041-65-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-bis(4-fluorophenyl)propyl-2-yn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-bis(4-fluorophenyl)propyl-2-yn-1-one(1420041-65-1)
• EPA Substance Registry System: 1,3-bis(4-fluorophenyl)propyl-2-yn-1-one(1420041-65-1)

Safety Data

• Hazardous Substances Data: 1420041-65-1(Hazardous Substances Data)

Upstream product

• 95895-33-3 1-(bromoethynyl)-4-fluorobenzene 
• 352-34-1 4-fluoro-1-iodobenzene 
• 201230-82-2 carbon monoxide 
• 471-25-0 Propiolic acid 

Downstream Products

• 1493-51-2 1,3-bis-(4-fluoro-phenyl)-1,3-propanedione 
• 62375-96-6 C₁₅H₁₀F₂O₂ 
• 1420041-47-9 (E)-3-fluoro-1,3-bis(4-fluorophenyl)prop-2-en-1-one 
• 1420041-46-8 (Z)-3-fluoro-1,3-bis(4-fluorophenyl)prop-2-en-1-one 

Relevant articles and documents

Alkyne derivative as well as preparation method and application thereof (by machine translation)

The invention belongs to the technical field of organic synthesis, and discloses an acetylenic ketone derivative and a preparation method and application thereof. The formula (I) is shown in the structural formula of the alkyne derivative. R1 And R2 Heterocyclyl groups of C1 - C20, halogen, ester, carbonyl, nitro, substituted amino, C5 - C30, or C5 - C30, respectively. To the strategy of nickel catalytic reduction coupling, a carboxylic acid derivative which is widely used in nature is used as a substrate, an alkyne halide is combined as an active alkynylation reagent, and under the condition of room temperature, the universality and the high efficiency method for rapidly constructing various substituted alkynes are obtained. The alkyne compound disclosed by the invention not only can be used as a practical synthesis, but also can be used as a precursor of heterocyclic compounds such as furan, pyrazole, quinoline, pyrimidine and the like. (by machine translation)