95895-33-3

Basic information

• Product Name: Benzene, 1-(bromoethynyl)-4-fluoro-
• CAS NO: 95895-33-3
• Molecular Formula: C8H4BrF
• Molecular Weight: 199.022
• Mol File: 95895-33-3.mol
• Article Data: 46

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(bromoethynyl)-4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(bromoethynyl)-4-fluoro-(95895-33-3)
• EPA Substance Registry System: Benzene, 1-(bromoethynyl)-4-fluoro-(95895-33-3)

Safety Data

• Hazardous Substances Data: 95895-33-3(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 706-06-9 3-(4-flurophenyl)prop-2-ynoic acid 
• 766-98-3 1-ethynyl-4-fluorobenzene 
• 159957-00-3 1-(2,2-dibromovinyl)-4-fluorobenzene 

Downstream Products

• 1206482-96-3 2-(4-fluoro-phenylethynyl)-5-phenyl-oxazole 
• 1231256-15-7 (E)-5-bromo-4-(2-(4-fluorophenyl)ethynyl)hept-4-en-3-ol 
• 1231255-98-3 1-((Z)-4-bromo-3-propylhept-3-en-1-ynyl)-4-fluorobenzene 
• 55606-94-5 1,4-bis(4'-fluorophenyl)-buta-1,3-diyne 
• 1258403-24-5 1-((Z)-2-bromo-1-iodovinyl)-4-fluorobenzene 
• 37859-33-9 2-(4-fluorobenzyl)benzo[d]thiazole 
• 1268700-01-1 (5-chlorobenzo[d]thiazol-2-yl)(4-fluorophenyl)methanone 
• 885900-99-2 N,N-diethyl-2-(4-fluorophenyl)acetamide 
• 101993-20-8 2-(4-fluorophenyl)-5-nitro-1-benzofuran 
• 1395418-46-8 1-butyl-2-(4-fluorophenyl)-1H-quinolin-4-one 
• 1395418-36-6 1-(2-chlorophenyl)-3-(4-fluorophenyl)propyn-1-one 
• 1429308-95-1 N-[2-(tert-butyldimethylsilyloxymethyl)allyl]-N-tert-butoxycarbonyl-(4-fluorophenyl)ethynylamine 
• 1449517-06-9 C₁₅H₁₀BrFN₂ 
• 782-17-2 2-(4-fluorophenyl)indole 

Relevant articles and documents

Palladium-Catalyzed Carbonylation in the Synthesis of N-Ynonylsulfoximines

Palladium-catalyzed carbonylation reactions with Cr(CO)6 as carbonyl source are key for the preparation of N-ynonylsulfoximines from NH-sulfoximines and bromoalkynes. The couplings proceed at room temperature with a wide range of substrate combinations affording the corresponding products in good yields. (Figure presented.).

Visible-Light-Promoted Formation of C—C and C—P Bonds Derived from Evolution of Bromoalkynes under Additive-Free Conditions: Synthesis of 1,1-Dibromo-1-en-3-ynes and Alkynylphosphine Oxides

The controllable achievement of C—C and C—P bond formations is developed via visible-light-promoted bromoalkyne dimerization or its further transformation with secondary phosphine oxides. The 1,1-dibromo-1-en-3-ynes are formed when bromoalkyne is exposed to visible-light. While alkynylphosphine oxides are generated when bromoalkynes are mixed with secondary phosphine oxides.

Catalytic Synthesis of Dibenzazepines and Dibenzazocines by 7-Exo- and 8-Endo-Dig-Selective Cycloisomerization

The 7-exo- and 8-endo-dig-selective gold-catalyzed cycloisomerizations of 2-propargylamino biphenyl derivatives were developed. The reaction of terminal alkynes gave dibenzo[b,d]azepines by 7-exo-dig cycloisomerization. In contrast, when internal alkynes were subjected to the reaction, 8-endo-dig cycloisomerization proceeded to provide dibenzo[b,d]azocines. The nucleophilicity at the reaction site and the electron-withdrawing effect of a tosyl group were important for the present selective transformation. This protocol could be used for ynamide substrates and a silver-catalyzed reaction gave 7-exo-dig products selectively.