1421504-06-4Relevant articles and documents
Synthesis of phenanthridine derivatives by microwave-mediated cyclization of o-furyl(allylamino)arenes
Read, Matthew Lovell,Gundersen, Lise-Lotte
, p. 1311 - 1316 (2013/03/29)
A novel and efficient synthesis of phenanthridines and aza analogues is reported. The key step is a microwave-mediated intramolecular Diels-Alder cyclization of o-furyl(allylamino)arenes. In the presence of a catalytic amount of acid, the DA-adduct reacts further to give the dihydrophenanthridines, which easily can be oxidized to fully aromatic compounds by air in the presence of UV light or by DDQ.
