1422044-24-3

Basic information

• Product Name: C₂₈H₄₅NO₄SSi
• Synonyms: C₂₈H₄₅NO₄SSi
• CAS NO: 1422044-24-3
• Molecular Weight: 519.821
• Mol File: 1422044-24-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₈H₄₅NO₄SSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₈H₄₅NO₄SSi(1422044-24-3)
• EPA Substance Registry System: C₂₈H₄₅NO₄SSi(1422044-24-3)

Safety Data

• Hazardous Substances Data: 1422044-24-3(Hazardous Substances Data)

Upstream product

• 81582-94-7 4-(-phenylsulfonyl)-1,2-epoxybutane 
• 873-55-2 sodium benzenesulfonate 
• 67100-44-1 (but-3-en-1-ylsulfonyl)benzene 
• 1422044-22-1 C₃₄H₅₉N₃O₅SSi₂ 
• 1422044-20-9 C₁₉H₂₅N₃O₅S 
• 1422044-19-6 C₂₈H₃₆O₈S₂ 
• 1422044-18-5 C₁₉H₂₆O₆S 
• 1422044-17-4 C₂₂H₃₀O₆S 
• 80522-42-5 triisopropylsilyl trifluoromethanesulfonate 
• 115369-27-2 R-1-(benzenesulfonyl)-butane-3,4-diol 
• 1422044-12-9 C₁₃H₁₈O₄S 
• 1422044-23-2 C₃₄H₅₉NO₄SSi₂ 

Relevant articles and documents

Unified Synthesis of 10-Oxygenated Lycopodium Alkaloids: Impact of C10-Stereochemistry on Reactivity

The pronounced impact of the C10 stereochemistry on the successful construction of a polycyclic Lycopodium alkaloid scaffold has been explored. A wide range of reaction conditions and functionality were investigated to control a keto sulfone Michael addition to construct the C7-C12 linkage. An unexpected, overriding impact of the C10 stereochemistry in stereoselectivity and reaction rate in the Michael addition was observed. Furthermore, divergent reactivity of a conformationally accelerated, intramolecular Mannich cyclization based on the C10 stereochemistry was discovered. The successful execution of this synthetic route resulted in the total synthesis of all three known 10-oxygenated Lycopodium alkaloids: 10-hydroxylycopodine, paniculine, and deacetylpaniculine.