81582-94-7

Basic information

• Product Name: 4-(-phenylsulfonyl)-1,2-epoxybutane
• Synonyms: 4-(-phenylsulfonyl)-1,2-epoxybutane
• CAS NO: 81582-94-7
• Molecular Weight: 212.269
• Mol File: 81582-94-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 4-(-phenylsulfonyl)-1,2-epoxybutane(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(-phenylsulfonyl)-1,2-epoxybutane(81582-94-7)
• EPA Substance Registry System: 4-(-phenylsulfonyl)-1,2-epoxybutane(81582-94-7)

Safety Data

• Hazardous Substances Data: 81582-94-7(Hazardous Substances Data)

Upstream product

• 115369-27-2 R-1-(benzenesulfonyl)-butane-3,4-diol 
• 873-55-2 sodium benzenesulfonate 
• 3112-85-4 methylphenylsulfonate 
• 118149-32-9 ((phenylsulfonyl)methyl)magnesium bromide 
• 106-89-8 epichlorohydrin 
• 3132-64-7 1,2-Epoxy-3-bromopropane 

Downstream Products

• 81599-94-2 Methanesulfonic acid (1S,2R)-2-benzenesulfonyl-cyclopropylmethyl ester 
• 81583-42-8 1,3-diiodo-1-(phenylsulfonyl)cyclobutane 
• 1422044-17-4 C₂₂H₃₀O₆S 
• 1422044-18-5 C₁₉H₂₆O₆S 
• 1422044-20-9 C₁₉H₂₅N₃O₅S 
• 1422044-22-1 C₃₄H₅₉N₃O₅SSi₂ 
• 1422044-23-2 C₃₄H₅₉NO₄SSi₂ 
• 1422044-24-3 C₂₈H₄₅NO₄SSi 
• 115369-27-2 R-1-(benzenesulfonyl)-butane-3,4-diol 
• 1422044-12-9 C₁₃H₁₈O₄S 

Relevant articles and documents

Photochemical Strain-Release-Driven Cyclobutylation of C(sp3)-Centered Radicals

A new photoredox-catalyzed decarboxylative radical addition approach to functionalized cyclobutanes is described. The reaction involves an unprecedented formal Giese-type addition of C(sp3)-centered radicals to highly strained bicyclo[1.1.0]but

Unified Synthesis of 10-Oxygenated Lycopodium Alkaloids: Impact of C10-Stereochemistry on Reactivity

The pronounced impact of the C10 stereochemistry on the successful construction of a polycyclic Lycopodium alkaloid scaffold has been explored. A wide range of reaction conditions and functionality were investigated to control a keto sulfone Michael addition to construct the C7-C12 linkage. An unexpected, overriding impact of the C10 stereochemistry in stereoselectivity and reaction rate in the Michael addition was observed. Furthermore, divergent reactivity of a conformationally accelerated, intramolecular Mannich cyclization based on the C10 stereochemistry was discovered. The successful execution of this synthetic route resulted in the total synthesis of all three known 10-oxygenated Lycopodium alkaloids: 10-hydroxylycopodine, paniculine, and deacetylpaniculine.

Chiral non-racemic dihydroxysulfones via hydrolytic kinetic resolutions - Synthesis of oxacyclic ring systems using intramolecular acylation strategies

A number of chiral non-racemic 1,2-dihydroxysulfones have been prepared in good yields and high enantiomeric excesses by hydrolytic kinetic resolution of the corresponding epoxysulfones with Jacobsen's (S,S)-salen(Co)III(OAc) catalyst. The intramolecular cyclization reactions of the acyl and ethoxycarbonyl derivatives of these dihydroxysulfones have been exploited to access a variety of functionalized chiral non-racemic cyclic ethers and lactones in good yields.