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1425049-37-1

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1425049-37-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1425049-37-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,5,0,4 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1425049-37:
(9*1)+(8*4)+(7*2)+(6*5)+(5*0)+(4*4)+(3*9)+(2*3)+(1*7)=141
141 % 10 = 1
So 1425049-37-1 is a valid CAS Registry Number.

1425049-37-1Downstream Products

1425049-37-1Relevant articles and documents

SELECTIVE INHIBITORS AND ALLOSTERIC ACTIVATORS OF SPHINGOSINE KINASE

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Page/Page column 52-53; 60, (2014/08/19)

Sphingosine 1-phosphate (S1P) is involved in hyper-proliferative diseases, such as cancer and vascular remodeling in pulmonary arterial hypertension. Inhibitors of sphingosine kinase 1 and 2 (SK1 and SK2), which catalyze the synthesis of S1P, may be useful anti- proliferative agents. We have synthesized a series of sphingosine-based inhibitors of SK and SK2. Also provided in this invention are compounds that activate SK1 which can be used in diseases such as fibrosis, where intracellular S1P is anti-fibrotic.

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