14259-45-1 Usage
Description
Asperuloside, an iridoid glycoside, is a bioactive compound isolated from various plant sources such as Galium verum, Paederia foetida, and G. tunetanum. It exhibits a range of biological activities, including anti-angiogenic, anti-inflammatory, and anti-obesity properties. Asperuloside is also recognized as an inhibitor of xanthine oxidase, which contributes to its therapeutic potential in treating various disorders.
Uses
Used in Pharmaceutical Applications:
Asperuloside is used as a therapeutic agent for the treatment of inflammatory and cardiovascular diseases. Its anti-inflammatory properties help in reducing the production of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6, which are involved in the pathogenesis of these conditions.
Used in Anti-angiogenic Applications:
Asperuloside is employed as an anti-angiogenic agent, inhibiting the formation of new blood vessels by reducing microvessel formation in chick embryo chorioallantoic membrane assays. This property makes it a potential candidate for the treatment of disorders characterized by abnormal blood vessel growth, such as certain types of cancer.
Used in Anti-obesity Applications:
Asperuloside is used as an anti-obesity agent, as demonstrated by its ability to decrease body weight gain, white adipose tissue (WAT) weight, and the ratio of WAT weight to body weight in a high-fat diet-induced mouse model of metabolic syndrome. This suggests that Asperuloside could be a valuable component in the development of treatments for obesity and related metabolic disorders.
Used in Xanthine Oxidase Inhibition:
Asperuloside is used as an inhibitor of xanthine oxidase, an enzyme involved in the purine metabolism pathway. Its inhibition can help in the management of conditions associated with elevated levels of uric acid, such as gout and hyperuricemia.
Check Digit Verification of cas no
The CAS Registry Mumber 14259-45-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,2,5 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14259-45:
(7*1)+(6*4)+(5*2)+(4*5)+(3*9)+(2*4)+(1*5)=101
101 % 10 = 1
So 14259-45-1 is a valid CAS Registry Number.