142696-01-3

Basic information

• Product Name: (2S,4S)-(+)-cis-4-acetoxyflavan
• Synonyms: (2S,4S)-(+)-cis-4-acetoxyflavan
• CAS NO: 142696-01-3
• Molecular Weight: 268.312
• Mol File: 142696-01-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2S,4S)-(+)-cis-4-acetoxyflavan(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-(+)-cis-4-acetoxyflavan(142696-01-3)
• EPA Substance Registry System: (2S,4S)-(+)-cis-4-acetoxyflavan(142696-01-3)

Safety Data

• Hazardous Substances Data: 142696-01-3(Hazardous Substances Data)

Upstream product

• 20755-09-3 (+/-)-cis-flavan-4-ol acetate 
• 108-05-4 vinyl acetate 
• 487-25-2 cis-4-hydroxyflavan 
• 487-26-3 Flavanone 
• 64-19-7 acetic acid 
• 487-25-2 2',4-dihydroxydihydrochalcone 
• 1214-47-7 1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 
• 525-82-6 FLAVONE 
• 108-24-7 acetic anhydride 

Downstream Products

• 41886-75-3 (2R,4R)-(-)-cis-4-hydroxyflavan 
• 55568-97-3 (2R,3R)-3-hydroxyflavanone 
• 476310-80-2 (2R,4R)-flavan-4-ol acetate 
• 487-26-3 (2S)-flavanone 
• 487-26-3 (R)-flavanone 
• 14051-53-7 flavylium ion 
• 96790-73-7 (2S,3S)-3-hydroxyflavanone 
• 192221-56-0 Acetic acid (2S,4S)-2-hydroxy-2-phenyl-chroman-4-yl ester 
• 51196-83-9 (2S,4S)-(+)-cis-4-hydroxyflavan 

Relevant articles and documents

Lipase-catalyzed kinetic resolution of (+/-)-cis-flavan-4-ol and its acetate: synthesis of chiral 3-hydroxyflavanones.

Lipase-catalyzed kinetic resolution of (+/-)-cis-flavan-4-ol and its acetate led to enantiomerically enriched flavan-4-ol and its acetate. These chiral compounds were converted to (2R, 3R)- and (25, 3S)-3-hydroxyflavanones.

Enzymatic Kinetic Resolution of Flavanone and cis-4-Acetoxyflavan

The microbial, asymmetric reduction of flavanone with fermenting bakers' yeast led to the formation of (2S,4S)-(+)-cis-4-hydroxyflavan and (2R)-(+)-flavanone.The kinetic resolution of racemic cis-4-acetoxyflavan with lipase PS yields (2R,4R)-(-)-cis-4-hydroxyflavan, and the (2S,4S)-(+)-enantiomer remains as the acetate.