142739-41-1

Basic information

• Product Name: Benzenemethanol, 4-fluoro-a-(phenylethynyl)-
• CAS NO: 142739-41-1
• Molecular Formula: C15H11FO
• Molecular Weight: 226.25
• Mol File: 142739-41-1.mol
• Article Data: 38

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-fluoro-a-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-fluoro-a-(phenylethynyl)-(142739-41-1)
• EPA Substance Registry System: Benzenemethanol, 4-fluoro-a-(phenylethynyl)-(142739-41-1)

Safety Data

• Hazardous Substances Data: 142739-41-1(Hazardous Substances Data)

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 4440-01-1 lithium phenylacetylide 
• 28995-88-2 1-methyl-4-((phenylethynyl)sulfonyl)benzene 
• 6738-06-3 phenylethynylmagnesium bromide 
• 591-50-4 iodobenzene 
• 3798-61-6 1-(4-fluorophenyl)prop-2-yn-1-ol 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 536-74-3 phenylacetylene 

Downstream Products

• 1032650-03-5 N-benzyl-1-(4-fluorophenyl)-3-phenylprop-2-yn-1-amine 
• 1056442-11-5 4-[1-(4-fluorophenyl)-3-phenylprop-2-ynyl]-2-methylphenol 
• 1056442-10-4 4-[1-(4-fluorophenyl)-3-phenylprop-2-ynyl]phenol 
• 1254977-16-6 5-fluoro-3-phenyl-1H-indene 
• 1222012-54-5 dimethyl (5-fluoro-1-oxo-3-phenyl-1H-inden-2-yl)phosphonate 
• 1373253-65-6 1-(4-fluorophenyl)-3-phenyl-3-(1H-pyrazol-1-yl)propan-1-one 
• 1439382-77-0 2-[1-(p-fluorophenyl)-3-phenylprop-2-yn-1-yl]-p-tolylsulfonylhydrazine 
• 1443443-21-7 dimethyl 5-benzyl-4-(4-fluorophenyl)-1-phenyl-1H-pyrrole-2,3-dicarboxylate 
• 1443443-23-9 dimethyl 5-benzyl-4-(4-fluorophenyl)-1-(p-tolyl)-1H-pyrrole-2,3-dicarboxylate 
• 1443443-25-1 dimethyl 5-benzyl-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-1H-pyrrole-2,3-dicarboxylate 
• 1262229-84-4 C₃₀H₂₀FNO₂ 
• 1262229-65-1 C₁₇H₁₂FNO₂ 
• 134747-51-6 trans-1-(4-fluorophenyl)-3-phenylprop-2-en-1-ol 
• 1618678-04-8 ethyl 1-phenyl-2-methyl-4-(4-fluorophenyl)-5-benzyl-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Visible Light-Induced Reductive Alkynylation of Aldehydes by Umpolung Approach

Reductive alkynylation of aldehydes by the Umpolung approach was developed using a photoredox catalyst under blue LED irradiation. Ketyl radicals, generated by single-electron reduction of aldehydes through proton-coupled electron transfer (PCET), reacted with electrophilic alkynylsulfones. Sterically demanding bulky aldehydes reacted smoothly under the Umpolung reaction conditions. Moreover, the alkynylation proceeded chemoselectively with an aryl aldehyde group in the presence of other carbonyl groups including an aliphatic aldehyde group.

Enantioselective [3 + 2] annulation of 4-isothiocyanato pyrazolones and alkynyl ketones under organocatalysis

An asymmetric [3 + 2] annulation reaction of 4-isothiocyanato pyrazolones with alkynyl ketones in the presence of an organic catalyst derived from a cinchona alkaloid under mild conditions is realized. This protocol provides unprecedented expeditious access to a wide range of optically active spiro[pyrroline-pyrazolones] with various electronic properties in high yields with good to excellent enantioselectivities.

Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.