1429122-63-3

Basic information

• Product Name: (4-chlorophenyl)(3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-en-7-yl)methanone
• Synonyms: (4-chlorophenyl)(3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-en-7-yl)methanone
• CAS NO: 1429122-63-3
• Molecular Weight: 353.848
• Mol File: 1429122-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-chlorophenyl)(3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-en-7-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-chlorophenyl)(3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-en-7-yl)methanone(1429122-63-3)
• EPA Substance Registry System: (4-chlorophenyl)(3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-en-7-yl)methanone(1429122-63-3)

Safety Data

• Hazardous Substances Data: 1429122-63-3(Hazardous Substances Data)

Upstream product

• 1429122-62-2 tert-butyl 3-phenyl-1-oxa-7-azaspiro[4.5]dec-2-ene-7-carboxylate 
• 122-01-0 4-chloro-benzoyl chloride 
• 1429121-55-0 tert-butyl 3-hydroxy-3-[3-(trimethylsilyl)prop-2-yn-1-yl]piperidine-1-carboxylate 
• 1429122-61-1 tert-butyl 3-{[(trifluoromethyl)sulfonyl]oxy}-1-oxa-7-azaspiro[4.5]dec-2-ene-7-carboxylate 
• 1160246-89-8 tert-butyl 3-oxo-1-oxa-7-azaspiro[4.5]decane-7-carboxylate 
• 98977-36-7 3-oxo-piperidine-1-carboxylic acid tert-butyl ester 
• 1429121-56-1 tert-butyl 3-hydroxy-3-(prop-2-yn-1-yl)piperidine-1-carboxylate 

Relevant articles and documents

Skeletal diversification via heteroatom linkage control: Preparation of bicyclic and spirocyclic scaffolds from N-substituted homopropargyl alcohols

The discovery and application of a new branching pathway synthesis strategy that rapidly produces skeletally diverse scaffolds is described. Two different scaffold types, one a bicyclic iodo-vinylidene tertiary amine/tertiary alcohol and the other, a spirocyclic 3-furanone, are each obtained using a two-step sequence featuring a common first step. Both scaffold types lead to intermediates that can be orthogonally diversified using the same final components. One of the scaffold types was obtained in sufficiently high yield that it was immediately used to produce a 97-compound library.