14310-34-0

Basic information

• Product Name: 1,2-bis(2-methoxyphenyl)ethane
• Synonyms: 1,2-bis(2-methoxyphenyl)ethane
• CAS NO: 14310-34-0
• Molecular Weight: 242.318
• Mol File: 14310-34-0.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: 1,2-bis(2-methoxyphenyl)ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-bis(2-methoxyphenyl)ethane(14310-34-0)
• EPA Substance Registry System: 1,2-bis(2-methoxyphenyl)ethane(14310-34-0)

Safety Data

• Hazardous Substances Data: 14310-34-0(Hazardous Substances Data)

Upstream product

• 606-45-1 2-methoxybenzoic acid methyl ester 
• 74587-13-6 phenylacetic o-methoxyphenylacetic anhydride 
• 90-02-8 salicylaldehyde 
• 27946-59-4 1-(2-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide 
• 106-38-7 para-bromotoluene 
• 612-16-8 (2-methoxyphenyl)methanol 
• 7035-11-2 4-chloro-2-chloromethyl-1-methoxy-benzene 
• 762-72-1 allyl-trimethyl-silane 
• 75-09-2 dichloromethane 
• 16750-63-3 2-methoxyphenylmagnesium bromide 
• 5396-38-3 1-(tert-butyl)-4-methoxybenzene 
• 22252-73-9 2-chloromethyl-4-tert-butylanisole 
• 130073-07-3 1,1-bis-(2-methoxyphenyl)ethanol 
• 5293-93-6 β,β-bis(o-methoxyphenyl)vinyl bromide 

Downstream Products

• 69198-06-7 2,2'-ethanediyl-bis-cyclohexanol 
• 92369-25-0 1,2-dicyclohexan-2-one-1-ylethane 
• 874487-47-5 4,4'-dioxo-4,4'-(6,6'-dimethoxy-bibenzyl-3,3'-diyl)-di-butyric acid 
• 2789-88-0 1,2-bis(4-methylphenyl)acetylene 
• 29338-20-3 1,2-bis-(2'-hydroxyphenyl)ethane 

Relevant articles and documents

2,2'-Dimethoxybibenzyl

The 2,2'-dimethoxybibenzyl molecule, C16H18O2, has the midpoint of the -CH2-CH2- bond on an inversion centre.Each benzene ring deviates slightly from planarity, shows marked angular distortion and is inclined at 81.5(1) deg to the plane of the C(Ar)-CH2-CH2-moiety.

A Bisphenolic Honokiol Analog Outcompetes Oral Antimicrobial Agent Cetylpyridinium Chloride via a Membrane-Associated Mechanism

Targeting Streptococcus mutans is the primary focus in reducing dental caries, one of the most common maladies in the world. Previously, our groups discovered a potent bactericidal biaryl compound that was inspired by the natural product honokiol. Herein, a structure activity relationship (SAR) study to ascertain structural motifs key to inhibition is outlined. Furthermore, mechanism studies show that bacterial membrane disruption is central to the bacterial growth inhibition. During this process, it was discovered that analog C2 demonstrated a 4-fold better therapeutic index compared to the commercially available antimicrobial cetylpyridinium chloride (CPC) making it a viable alternative for oral care.

Nickel catalyzed deoxygenative cross-coupling of benzyl alcohols with aryl-bromides

A nickel-catalyzed cross-electrophile coupling of benzyl alcohols with aromatic bromides has been developed. This deoxygenative cross-coupling occurs under mild reaction conditions at ambient temperature affording diarylmethanes, or 1,3-diarylpropenes from benzyl allyl alcohols. The system demonstrated good chemoselectivity tolerating an assortment of reactive functional groups.