143264-54-4 Usage
General Description
(S)-1-Cbz-2-(2-Oxoethyl)Piperidine is a chemical compound that consists of a piperidine molecule with a Cbz (benzyloxycarbonyl) protecting group at the nitrogen atom and a 2-oxoethyl substituent at the second carbon atom. The compound is commonly used in organic synthesis and medicinal chemistry as a building block for the construction of various pharmaceuticals and biologically active molecules. It has the potential to act as a chiral intermediate for the synthesis of numerous drug candidates and can be further functionalized to introduce additional chemical moieties or modify its pharmacological properties. The compound’s unique structure and reactivity make it a valuable tool for the preparation of diverse molecular entities with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 143264-54-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,2,6 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143264-54:
(8*1)+(7*4)+(6*3)+(5*2)+(4*6)+(3*4)+(2*5)+(1*4)=114
114 % 10 = 4
So 143264-54-4 is a valid CAS Registry Number.
143264-54-4Relevant articles and documents
Improved protocol for asymmetric, intramolecular heteroatom Michael addition using organocatalysis: Enantioselective syntheses of homoproline, pelletierine, and homopipecolic acid
Carlson, Erik C.,Rathbone, Lauren K.,Yang, Hua,Collett, Nathan D.,Carter, Rich G.
, p. 5155 - 5158 (2008/09/21)
(Chemical Equation Presented) An improved protocol for the construction of enantioenriched pyrrolidine, indoline, and piperidine rings using an organocatalyzed, intramolecular heteroatom Michael addition is described. Application to the enantioselective synthesis of homoproline, homopipecolic acid, and pelletierine has been accomplished.
Diastereofacial Selectivity in Intermolecular Nitrone Cycloadditions to Chiral Allyl Ethers. Application to Chiral Synthesis of Coniine
Ito, Masayuki,Maeda, Masae,Kibayashi, Chihiro
, p. 3765 - 3768 (2007/10/02)
The intermolecular cycloadditions of a cyclic nitrone to chiral allyl ethers take place with erythro selectivity, where the degree of selectivity achieved is dependent upon the size of the alkyl substituent attached to the allylic chiral center, and these reactions are applied to the synthesis of optically active alkaloid coniine.
