143325-87-5Relevant articles and documents
Tetrahydroxynaphthalene reductase: Catalytic properties of an enzyme involved in reductive asymmetric naphthol dearomatization
Schaetzle, Michael A.,Flemming, Stephan,Husain, Syed Masood,Richter, Michael,Guenther, Stefan,Mueller, Michael
, p. 2643 - 2646 (2012/05/04)
In reduced circumstances: Tetrahydroxynaphthalene reductase shows a broad substrate range including alternate phenolic compounds and cyclic ketones. Structural modeling reveals major enzyme-substrate interactions; C-terminal truncation of the enzyme causes an altered substrate preference, in accordance with stabilization of the substrate by the C-terminal carboxylate (see picture). This effect allows the identification of a homologous enzyme. Copyright
THE SYNTHESIS AND IDENTIFICATION OF ISOMERIC PRODUCTS OF ENZYMATIC O-DEMETHYLATION OF THE SYMPATHOMIMETIC TETRAMINOL - trans-3-(2-HYDROXYETHYLAMINO)-5,8-DIMETHOXY-1,2,3,4-TETRAHYDRO-2-NAPHTHOL
Drandarov, Konstantin
, p. 1111 - 1126 (2007/10/02)
The structure of the positional isomers of mono-O-demethylated metabolites (V and VI) of Tetraminol - trans-3-(2-hydroxyethylamino)-5,8-dimethoxy-1,2,3,4-tetrahydro-2-naphthol (XIX) - and the pairs of related derivatives was determined.
Tetrahydronaphthyloxy-aminopropanols and salts thereof
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, (2008/06/13)
This invention relates to new tetrahydronaphthyloxy-aminopropanols and related compounds of the formula SPC1 And to salts of such compounds, which are useful in coronary diseases.